1.1: HCl gas / acetonitrile / 0.5 h / 0 - 20 °C 1.2: acetonitrile / 2 h / -10 - 0 °C 1.3: 86.5 percent / acetonitrile / 1 h / -10 - 0 °C 2.1: 75 percent / t-BuOK / tetrahydrofuran / -5 - 45 °C View Scheme
参考文献
Faul, Margaret M.; Gillig, James R.; Jirousek, Michael R.; Ballas, Lawrence M.; Schotten, Theo; Kahl, Astrid; Mohr, Michael
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 11 p. 1857 - 1859
2,3-dicyano-5,6-dichloro-p-benzoquinone in tetrahydrofuran
T=0 - 5°C; 1 h;
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
potassium carbonate in N,N-dimethyl-formamide
T=20 - 50°C; 5 h;
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
sodium tris(acetoxy)borohydride in acetic acid
T=20 - 60°C;
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
1: 83 percent / NaBH(OAc)3 / acetic acid / 19 h / 20 - 50 °C
2: 98 percent / H2 / Pd/C / methanol / 20 h / 2585.74 Torr
3: 97 percent / K2CO3 / dimethylformamide / 5 h / 20 - 50 °C
View Scheme
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
1: 85 percent / NaBH(OAc)3 / acetic acid / 3 h / 20 °C
2: 90 percent / DDQ / tetrahydrofuran / 1 h / 0 - 5 °C
View Scheme
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
1: 99 percent / NaBH(OAc)3 / acetic acid / 1 h / 20 °C
2: 88 percent / DDQ / tetrahydrofuran / 0.75 h / 0 - 5 °C
3: 70 percent / TFA / ethyl acetate / 12 h / 60 °C
4: 97 percent / K2CO3 / dimethylformamide / 5 h / 20 - 50 °C
View Scheme
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
