2,3-二氯-4-硝基苯酚合成路线 （共 5 条）
反应条件
TrOOH; potassium tert-butylate in ammonia
T=-33°C;
参考文献
Makosza, Mieczyslaw; Sienkiewicz, Krzysztof
Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4199 - 4208
反应条件
nitric acid in acetic acid
参考文献
Eli Lilly and Company
Patent: US4614807 A1, 1986 ;
反应条件
nitric acid in acetic anhydride; acetic acid
T=4 - 8°C; 1 h;
参考文献
Harada; Matsushita; Yodo; Nakamura; Yonetani
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 8 p. 3215 - 3226
反应条件
TrOOH; potassium tert-butylate in ammonia
T=-33°C;
参考文献
Makosza, Mieczyslaw; Sienkiewicz, Krzysztof
Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4199 - 4208
反应条件
sodium hydroxide; sulfuric acid; nitric acid
1.) 5 deg C, 2 h, 2.) H2O, 80 deg C, 0.5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Morita, Seiji; Kitano, Kazuyoshi; Matsubara, Jun; Ohtani, Tadaaki; Kawano, Yoshikazu; Otsubo, Kenji; Uchida, Minoru
Tetrahedron, 1998 , vol. 54, # 19 p. 4811 - 4818
