4-(4-甲氧基苯基)吡啶合成路线 （共 33 条）
反应条件
8C33H27N9O3*6Pd(2+)*12NO3(1-); potassium carbonate in ethanol; water T=60°C; Suzuki-Miyaura Coupling; 10 h; Green chemistry;
参考文献
Green Chemistry, , vol. 15, # 11 p. 3150 - 3154
反应条件
bis(acetylacetonate)nickel(II); 1,2-bis-(diphenylphosphino)ethane in tetrahydrofuran T=20°C; Corriu-Kumada-Tamao coupling; 18 h;
参考文献
Tetrahedron, , vol. 61, # 13 p. 3261 - 3269
反应条件
3-benzyl-1-(2-hydroxy-2-phenylethyl)imidazolium chloride; tetrabutylammomium bromide; water; palladium diacetate; sodium hydroxide T=120°C; Hiyama coupling; 1 h; Microwave irradiation;
参考文献
European Journal of Organic Chemistry, , # 35 p. 7174 - 7181
反应条件
Cp2Ni; potassium tert-butylate; triphenylphosphine T=100°C; 12 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 11, # 12 p. 2679 - 2682
反应条件
potassium tert-butylate T=110°C; 8 h;
参考文献
New Journal of Chemistry, , vol. 38, # 2 p. 827 - 836
反应条件
hydrogenchloride; sodium nitrite
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 12 p. 2427 - 2432
反应条件
1.1: diisopropylamine; n-butyllithium / tetrahydrofuran; hexane / -95 °C 1.2: ZnCl2 / tetrahydrofuran; hexane / -95 - 20 °C 1.3: 48 percent / Pd(PPh3)4 / tetrahydrofuran / Heating 2.1: 81 percent / Rieke zinc / tetrahydrofuran / 1 h / Heating View Scheme
参考文献
Organic Letters, , vol. 3, # 6 p. 835 - 838
反应条件
1.1: diisopropylamine; n-butyllithium / tetrahydrofuran; hexane / -95 °C 1.2: ZnCl2 / tetrahydrofuran; hexane / -95 - 20 °C 1.3: 48 percent / Pd(PPh3)4 / tetrahydrofuran / Heating 2.1: 81 percent / Rieke zinc / tetrahydrofuran / 1 h / Heating View Scheme
参考文献
Organic Letters, , vol. 3, # 6 p. 835 - 838
反应条件
1: 1-bromo-4-methoxy-benzene With iodine; magnesium in tetrahydrofuran T=35°C; 3 h; Inert atmosphere; 2: 4-Chloro-pyridine With [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in toluene T=30 - 45°C; 4.25 h; Inert atmosphere;
参考文献
Organic Process Research and Development, , vol. 7, # 3 p. 436 - 445
反应条件
1,3-bis-(diphenylphosphino)propane; potassium carbonate; nickel dichloride in 1,4-dioxane T=100°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 16, # 17 p. 4991 - 4994
