4-(4-甲氧基苯基)吡啶合成路线 (共 33 条)
反应条件
sodium salt of phosphorous acid; palladium on activated charcoal in isopropyl alcohol T=80°C; Suzuki-Miyaura coupling reaction; 3 h;
参考文献
Chemical Communications, , # 47 p. 5069 - 5071
反应条件
sodium 2-(2-pyridin-3-ylethylamino)ethyl sulfonate; palladium dichloride in water T=20°C; Suzuki coupling; 3 h;
参考文献
Tetrahedron Letters, , vol. 49, # 41 p. 5858 - 5862
反应条件
tris(dibenzylideneacetone)dipalladium (0); [HP(t-Bu)3]BF4 in tetrahydrofuran T=175°C; Negishi cross-coupling; 0.166667 h; microwave irradiation;
参考文献
Chemical Communications, , # 5 p. 564 - 565
反应条件
palladium diacetate; triethylamine; tris-(o-tolyl)phosphine in acetonitrile T=125°C; 20 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 3 p. 694 - 695
反应条件
zinc in tetrahydrofuran 1 h; Heating;
参考文献
Organic Letters, , vol. 3, # 6 p. 835 - 838
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran Inert atmosphere; 2: 4-bromo-pyridine-hydrochloride With NiCl2((PPh3)P)2 in tetrahydrofuran T=10 - 50°C; Inert atmosphereCooling;
参考文献
Organic Process Research and Development, , vol. 7, # 3 p. 436 - 445
反应条件
palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine in ethylene glycol dimethyl ether; water T=80°C; Suzuki Coupling; 7 h; Inert atmosphere;
参考文献
Organic Process Research and Development, , vol. 7, # 3 p. 436 - 445
反应条件
potassium hydroxide; tetrabutylammomium bromide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 3 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 11 p. 4755 - 4763
反应条件
1: 4-hydroxy-pyridine With potassium phosphate; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate in 1,4-dioxane; N,N-dimethyl-formamide T=100°C; 3 h; Inert atmosphere; 2: (4-methoxyphenyl)-boronic acid With [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane; N,N-dimethyl-formamide T=100 - 110°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 17, # 14 p. 4038 - 4042
反应条件
potassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane T=100 - 110°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 9 p. 1543 - 1550