4-甲基-2-(1-哌嗪基)嘧啶合成路线 (共 6 条)
反应条件
in ethanol 1.) ice bath, 2.) room temperature;
参考文献
Ishizumi; Kojima; Antoku
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2288 - 2300
反应条件
sodium carbonate in water T=50 - 65°C;
参考文献
Journal of Chemical Research, , # 12 p. 809 - 811
反应条件
potassium carbonate in water T=50 - 65°C;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 58, # 9 p. 5515 - 5522
反应条件
1: 30percent aq. H2O2, HCOOH / Ambient temperature 2: 79 percent / ethanol / 1.) ice bath, 2.) room temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 9 p. 2288 - 2300
反应条件
1: aq. NaOH / Ambient temperature 2: 30percent aq. H2O2, HCOOH / Ambient temperature 3: 79 percent / ethanol / 1.) ice bath, 2.) room temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 9 p. 2288 - 2300
反应条件
1: hydrogenchloride; zinc(II) chloride; sodium nitrite / dichloromethane; water 2: potassium carbonate / water / 50 - 65 °C View Scheme
参考文献
Journal of Agricultural and Food Chemistry, , vol. 58, # 9 p. 5515 - 5522