(叔丁氧基羰基甲基)三苯基溴化鏻合成路线 （共 6 条）
反应条件
in benzene T=20°C; 12 h;
参考文献
UNIVERSITY OF SOUTH FLORIDA
Patent: US2007/265243 A1, 2007 ;
Location in patent: Page/Page column 4 ;
反应条件
1: sodium hydroxide 2: benzene / addition at o deg C, and for 16 h at room temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 43 p. 4959 - 4962
反应条件
sodium hydroxide in dichloromethane; water T=0 - 5°C; 0.25 h;
参考文献
Sajja, Eswaraiah; Vetukuri, Venkata Naga Kali Vara Prasada Raju; Ningam, Srinivas Reddy; Vedantham, Ravindra
Patent: US2007/43088 A1, 2007 ;
Location in patent: Page/Page column 8 ;
反应条件
sodium hydroxide in dichloromethane; water T=-5°C; 2.5 h; Large scale reaction; chemoselective reaction;
参考文献
Prasada Raju; Ravindra, Vedantham; Mathad, Vijayavitthal T.; Dubey; Reddy, Padi Pratap
Organic Process Research and Development, 2009 , vol. 13, # 4 p. 710 - 715
反应条件
1: (tert-butoxycarbonylmethyl)-triphenylphosphonium bromide; phthalic carbaldehyde With sodium hydroxide in dichloromethane; water T=-5 - -3°C; 2.75 h; Industry scale; 2: 3-amino-2-butenoic acid ethyl ester With trifluoroacetic acid in isopropyl alcohol T=-7°C; 2.75 h; 3: With sodium hydrogencarbonate in water; ethyl acetate; isopropyl alcohol T=0 - 25°C; 0.333333 h;
参考文献
Sajja, Eswaraiah; Vetukuri, Venkata Naga Kali Vara Prasada Raju; Ningam, Srinivas Reddy; Vedantham, Ravindra
Patent: US2007/43088 A1, 2007 ;
Location in patent: Page/Page column 6 ;
反应条件
potassium hydrogencarbonate in 1,4-dioxane; chloroform
Wittig reaction; Heating;
参考文献
Etzenhouser, Beth; Hansch, Corwin; Kapur, Sanjay; Selassie
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 1 p. 199 - 209
