4-氯-2-甲硫基嘧啶-5-羧酸乙酯合成路线

ORCHID RESEARCH LABORATORIES LTD; RAJAGOPAL, Sridharan; KILAMBI, Narasimhan; KACHHADIA, Virendra; RATHINASAMY, Suresh; BALASUBRAMANIAN, Gopalan; MANI, Umamaheswari; RAJAGOPALAN, Nirmala; PUSHPARAJ, Judy Auxcilia; ROY, Anshu Mittal; VISHWAKARMA, Lolaknath Santosh; NARAYANAN, Shridhar; KALIYAMOORTHY, Vadivel; THANASEKARAN, Ponpandian; THATAVARTHY KRISHNA, Rama; KANNAN, Kalaivani; KULATHINGAL, Jayanarayan; MOOKKAN, Jeyamurugan; CHIDAMBARAM VENKATESWARAN, Srinivasan; AHAMED ALI, Fakrudeen
Patent: WO2012/117421 A1, 2012 ;
WO 2012/117421 A1

5909-24-04-氯-2-甲硫基嘧啶-5-羧酸乙酯

185039-37-6N-[6-(2,6-二氯苯基)-8-甲基-2-(甲硫基)吡啶并[2,3-d]嘧啶-7(8H)-亚基]乙酰胺

参考文献

Klutchko, Sylvester R.; Hamby, James M.; Boschelli, Diane H.; Wu, Zhipei; Kraker, Alan J.; Amar, Aneesa M.; Hartl, Brian G.; Shen, Cynthia; Klohs, Wayne D.; Steinkampf, Randall W.; Driscoll, Denise L.; Nelson, James M.; Elliott, William L.; Roberts, Billy J.; Stoner, Chad L.; Vincent, Patrick W.; Dykes, Donald J.; Panek, Robert L.; Lu, Gina H.; Major, Terry C.; Dahring, Tawny K.; Hallak, Hussein; Bradford, Laura A.; Showalter, H. D. Hollis; Doherty, Annette M.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 17 p. 3276 - 3292

5909-24-04-氯-2-甲硫基嘧啶-5-羧酸乙酯+

1003-03-8环戊胺

211245-62-4

参考文献

WARNER-LAMBERT COMPANY LLC
Patent: WO2005/42519 A1, 2005 ;
Location in patent: Page/Page column 43 ;
WO 2005/042519 A1

5909-24-04-氯-2-甲硫基嘧啶-5-羧酸乙酯

211245-67-9

参考文献

Barvian; Boschelli; Cossrow; Dobrusin; Fattaey; Fritsch; Fry; Harvey; Keller; Garrett; La; Leopold; McNamara; Quin; Trumpp-Kallmeyer; Toogood; Wu; Zhang
Journal of Medicinal Chemistry, 2000 , vol. 43, # 24 p. 4606 - 4616