4,4-二甲基-2-戊酮合成路线 （共 111 条）
反应条件
lithium iodide in diethyl ether T=25°C; stopped-flow ultraviolet and infrared spectroscopy; reaction with halide-free lithium dimethylcuprate; kinetics and mechanism of the conjugate addition of lithium dimethylcuprate to α,β-unsaturated ketones, concentration dependence; Rate constantEquilibrium constant;
参考文献
Journal of the American Chemical Society, , vol. 103, p. 141
反应条件
zinc(II) chloride in dichloromethane T=22°C; 48 h;
参考文献
Reetz, Manfred T.; Maier, Wilhelm F.; Heimbach, Horst; Giannis, Athanassios; Anastassious, Georgia
Chemische Berichte, 1980 , vol. 113, # 12 p. 3734 - 3740
反应条件
zinc(II) chloride in dichloromethane T=22°C; 27 h; further reagents: TiCl4, SnCl4, ZrCl4, AlCl3;
参考文献
Reetz, Manfred T.; Maier, Wilhelm F.; Heimbach, Horst; Giannis, Athanassios; Anastassious, Georgia
Chemische Berichte, 1980 , vol. 113, # 12 p. 3734 - 3740
反应条件
para-toluenesulphonic acid silver salt in dichloromethane T=22°C; 15 h; ZnCl2;
参考文献
Reetz, Manfred T.; Maier, Wilhelm F.; Heimbach, Horst; Giannis, Athanassios; Anastassious, Georgia
Chemische Berichte, 1980 , vol. 113, # 12 p. 3734 - 3740
反应条件
titanium tetrachloride in dichloromethane T=-40°C; 4 h;
参考文献
Reetz, Manfred T.; Maier, Wilhelm F.; Heimbach, Horst; Giannis, Athanassios; Anastassious, Georgia
Chemische Berichte, 1980 , vol. 113, # 12 p. 3734 - 3740
反应条件
water; platinum (II) chloride in tetrahydrofuran T=60°C; 12 h; various catalysts; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 58, # 26 p. 7613 - 7614
反应条件
1: 95 percent / diethyl ether 2: 63 percent / di-tert-butyl hyponitrite / benzene / 2 h / 60 °C 3: 92 percent / aq. TBAF / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 8 p. 769 - 775
反应条件
1: 91 percent / sec-butyllithium / tetrahydrofuran 2: m-chloroperoxybenzoic acid / CH2Cl2 3: aq. H2SO4 / methanol / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 13, # 12 p. 969 - 976
反应条件
1: m-chloroperoxybenzoic acid / CH2Cl2 2: aq. H2SO4 / methanol / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 13, # 12 p. 969 - 976
反应条件
T=130 - 140°C; P=10297.1 Torr;
参考文献
Journal of the Chemical Society, , p. 2170,2177
Journal of the American Chemical Society, , vol. 80, p. 2497
