2-甲基-4-戊炔-2-醇合成路线 （共 24 条）
反应条件
1: 1.) BuLi / 1.) HMPA, hexane, 0 deg C, 40 min, 2.) HMPA, a.) 0-15 deg C, 18 h, b.) 40-50 deg C, 1 h
2: 230 mg / Na, liquid NH3 / 2 h / Heating
View Scheme
参考文献
Masamune, Tadashi; Sato, Shingo; Abiko, Atsushi; Ono, Mitsunori; Murai, Akio
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 10 p. 2895 - 2904
反应条件
quinoline; Petroleum ether
Hydrogenation.an Lindlar-Katalysator;
参考文献
Gutmann et al.
Helvetica Chimica Acta, 1959 , vol. 42, p. 719,720,726
反应条件
1: EtMgBr / tetrahydrofuran
2: MnO2 / diethyl ether
View Scheme
参考文献
Obrecht, Daniel
Helvetica Chimica Acta, 1991 , vol. 74, # 1 p. 27 - 46
反应条件
isopropylmagnesium chloride
1.) THF, r.t., 5 h, 2.) r.t., 12 h; Yield given. Multistep reaction;
参考文献
Obrecht, Daniel
Helvetica Chimica Acta, 1991 , vol. 74, # 1 p. 27 - 46
