N-(3-羟丙基)氨基甲酸叔丁酯合成路线 （共 36 条）
反应条件
in dichloromethane 12 h;
参考文献
Zeneca Limited; Zeneca Pharma S.A.
Patent: US6414148 B1, 2002 ;
US 6414148 B1
反应条件
Cp*RuCl{(C6H5)2P-(CH2)2NH2-κ2-P,N}; potassium tert-butylate; hydrogen in tert-butyl alcohol T=80°C; P=22502.3 Torr; 24 h; Autoclave;
参考文献
Ito, Masato; Koo, Lee Wei; Himizu, Akio; Kobayashi, Chika; Sakaguchi, Ayaka; Ikariya, Takao
Angewandte Chemie - International Edition, 2009 , vol. 48, # 7 p. 1324 - 1327
反应条件
in dichloromethane; triethylamine T=20°C; 3 h;
参考文献
F. HOFFMANN-LA ROCHE AG; GOODNOW JR., Robert Alan; HAMILTON, Matthew Michael; KOWALCZYK, Agnieszka; SIDDURI, Achyutharao
Patent: WO2013/110578 A1, 2013 ;
Location in patent: Page/Page column 46 ;
反应条件
in 4-(dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran
参考文献
Spirogen Limited
Patent: US2003/120069 A1, 2003 ;
反应条件
1-chloroethyl chlorocarbonate in methanol T=20°C; 0.416667 h;
参考文献
Yeom, Chang-Eun; Kim, Young Jong; Lee, So Young; Shin, Yong Je; Kim, B. Moon
Tetrahedron, 2005 , vol. 61, # 52 p. 12227 - 12237
反应条件
zinc(II) triflate in methanol T=20°C; 0.583333 h;
参考文献
Srinivasulu; Satyanarayana; Ravi Kumar
Russian Journal of General Chemistry, 2013 , vol. 83, # 12 p. 2419 - 2422
Zh. Obshch. Khim., 2013 , vol. 83, # 12 p. 2419 - 2422,4
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
Contino-Pepin, Christiane; Parat, Audrey; Perino, Sandrine; Lenoir, Christine; Vidal, Michel; Galons, Herve; Karlik, Stephen; Pucci, Bernard
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 3 p. 878 - 881
反应条件
sodium hydroxide in tetrahydrofuran
反应条件
2,6-dimethylpyridine; trichloromonobromomethane; Ir[(dF(CF3)ppy)2(dtbbpy)]PF6; water in acetonitrile 12 h; Inert atmosphereIrradiation; chemoselective reaction;
参考文献
Tucker, Joseph W.; Narayanam, Jagan M. R.; Shah, Pinkey S.; Stephenson, Corey R. J.
Chemical Communications, 2011 , vol. 47, # 17 p. 5040 - 5042
反应条件
triethylamine in tetrahydrofuran T=0 - 20°C; 15.1667 h;
参考文献
Millet, Anthony; Dailler, David; Larini, Paolo; Baudoin, Olivier
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2678 - 2682
Angew. Chem., 2014 , # 10 p. 2716 - 2720,5
