1,13-十四碳二烯-3-酮合成路线 （共 15 条）
反应条件
1: 95 percent / dimethylsulfoxide / 24 h
2: 1.) diisobutylaluminum hydride; 2.) HCl / 1.) benzene, hexane, 1 h; 2.) 0 deg C, MeOH, ether
3: 1.) Mg, I2, 1,2-dibromo-ethane / 1.) THF, reflux; 2.) THF, 0 deg C, 1 h
4: 76 percent / MnO2 / hexane / 24 h
View Scheme
参考文献
Spanton,S.G.; Prestwich,G.D.
Tetrahedron, 1982 , vol. 38, p. 1921
反应条件
1: 2) 2M HCl / 1) THF, HMPA, -78 to 20 deg C
2: MCPBA / CH2Cl2 / 0.17 h / -78 °C / sodium metaperiodate
3: CaCO3 / pyrolysis
View Scheme
参考文献
Tuchinda, Patoomratana; Prapansiri, Vichukorn; Naengchommong, Waree; Reutrakul, Vichai
Chemistry Letters, 1984 , p. 1427 - 1430
反应条件
1: MCPBA / CH2Cl2 / 0.17 h / -78 °C / sodium metaperiodate
2: CaCO3 / pyrolysis
View Scheme
参考文献
Tuchinda, Patoomratana; Prapansiri, Vichukorn; Naengchommong, Waree; Reutrakul, Vichai
Chemistry Letters, 1984 , p. 1427 - 1430
反应条件
T=640 - 670°C; P=0.75006 - 3.00024 Torr;
参考文献
Nagel, Matthias; Hansen, Hans-Juergen; Frater, Georg
Synlett, 2002 , # 2 p. 275 - 279
参考文献
Prestwich,G.D. et al.
Tetrahedron Letters, 1975 , # 52 p. 4701 - 4704
