4-氨基-1-哌啶甲酸乙酯合成路线

参考文献

Miriyala, Bruhaspathy; Bhattacharyya, Sukanta; Williamson, John S.
Tetrahedron, 2004 , vol. 60, # 7 p. 1463 - 1471

107618-03-13-(哌啶-4-基)-1H-咪唑并[4,5-b]吡啶-2(3H)-酮

参考文献

Burgey, Christopher S.; Stump, Craig A.; Nguyen, Diem N.; Deng, James Z.; Quigley, Amy G.; Norton, Beth R.; Bell, Ian M.; Mosser, Scott D.; Salvatore, Christopher A.; Rutledge, Ruth Z.; Kane, Stefanie A.; Koblan, Kenneth S.; Vacca, Joseph P.; Graham, Samuel L.; Williams, Theresa M.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5052 - 5056

58859-46-44-氨基-1-哌啶甲酸乙酯

53786-10-04-(2-酮基-3-甲基-1-苯并咪唑基)哌啶

参考文献

Gustin, Darin J.; Sehon, Clark A.; Wei, Jianmei; Cai, Hui; Meduna, Steven P.; Khatuya, Haripada; Sun, Siquan; Gu, Yin; Jiang, Wen; Thurmond, Robin L.; Karlsson, Lars; Edwards, James P.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 6 p. 1687 - 1691

58859-46-44-氨基-1-哌啶甲酸乙酯

53786-45-14-((2-氨基-4-氯苯基)氨基)哌啶-1-羧酸乙酯

参考文献

Burgey, Christopher S.; Stump, Craig A.; Nguyen, Diem N.; Deng, James Z.; Quigley, Amy G.; Norton, Beth R.; Bell, Ian M.; Mosser, Scott D.; Salvatore, Christopher A.; Rutledge, Ruth Z.; Kane, Stefanie A.; Koblan, Kenneth S.; Vacca, Joseph P.; Graham, Samuel L.; Williams, Theresa M.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5052 - 5056

58859-46-44-氨基-1-哌啶甲酸乙酯

53786-28-05-氯-1,3-二氢-1-(4-哌啶基)-2H-苯并咪唑-2-酮

参考文献

Burgey, Christopher S.; Stump, Craig A.; Nguyen, Diem N.; Deng, James Z.; Quigley, Amy G.; Norton, Beth R.; Bell, Ian M.; Mosser, Scott D.; Salvatore, Christopher A.; Rutledge, Ruth Z.; Kane, Stefanie A.; Koblan, Kenneth S.; Vacca, Joseph P.; Graham, Samuel L.; Williams, Theresa M.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5052 - 5056

58859-46-44-氨基-1-哌啶甲酸乙酯+

84946-20-31-(4-氟苄基)-2-氯苯并咪唑

84501-68-84-[[1-[(4-氟苯基)甲基]-1H-苯并咪唑-2-基]氨基]哌啶-1-甲酸乙酯

参考文献

Martin, Rainer E.; Green, Luke G.; Guba, Wolfgang; Kratochwil, Nicole; Christ, Andreas
Journal of Medicinal Chemistry, 2007 , vol. 50, # 25 p. 6291 - 6294

67-66-3氯仿+

58859-46-44-氨基-1-哌啶甲酸乙酯+

84946-20-31-(4-氟苄基)-2-氯苯并咪唑

84501-68-84-[[1-[(4-氟苯基)甲基]-1H-苯并咪唑-2-基]氨基]哌啶-1-甲酸乙酯

参考文献

Janssen Pharmaceutica N.V.
Patent: US4835161 A1, 1989 ;

58859-46-44-氨基-1-哌啶甲酸乙酯

84501-68-84-[[1-[(4-氟苯基)甲基]-1H-苯并咪唑-2-基]氨基]哌啶-1-甲酸乙酯

参考文献

Roman, Gheorghe; Crandall, Ian E.; Szarek, Walter A.
ChemMedChem, 2013 , vol. 8, # 11 p. 1795 - 1804

58859-46-44-氨基-1-哌啶甲酸乙酯+

84946-20-31-(4-氟苄基)-2-氯苯并咪唑

100460-87-51-(4-氟苄基)-1H-苯并[d]咪唑-2(3H)-酮+

84501-68-84-[[1-[(4-氟苯基)甲基]-1H-苯并咪唑-2-基]氨基]哌啶-1-甲酸乙酯

参考文献

Senanayake, Chris H.; Hong, Yaping; Xiang, Tingjian; Scott Wilkinson; Bakale, Roger P.; Jurgens, Alex R.; Pippert, Mark F.; Butler, Hal T.; Wald, Stephen A.
Tetrahedron Letters, 1999 , vol. 40, # 38 p. 6875 - 6879

58859-46-44-氨基-1-哌啶甲酸乙酯+

84946-20-31-(4-氟苄基)-2-氯苯并咪唑

100460-87-51-(4-氟苄基)-1H-苯并[d]咪唑-2(3H)-酮+

84501-68-84-[[1-[(4-氟苯基)甲基]-1H-苯并咪唑-2-基]氨基]哌啶-1-甲酸乙酯

参考文献

Senanayake, Chris H.; Hong, Yaping; Xiang, Tingjian; Scott Wilkinson; Bakale, Roger P.; Jurgens, Alex R.; Pippert, Mark F.; Butler, Hal T.; Wald, Stephen A.
Tetrahedron Letters, 1999 , vol. 40, # 38 p. 6875 - 6879