1-碘-3,4-亚甲基二氧基苯合成路线 （共 31 条）
反应条件
tetraethylammonium p-toluenesulfonate; triphenylphosphine; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide Pt anode/Pt cathode; electrolysis with 2.5 mA/cm2;
参考文献
Torii, Sigeru; Tanaka, Hideo; Hamatani, Takeshi; Morisaki, Kazuo; Jutand, Anny; et al.
Chemistry Letters, 1986 , p. 169 - 172
反应条件
potassium carbonate in methanol; pinacolate ester
参考文献
Commonwealth Scientific and Industrial Research Organization
Patent: US6448433 B1, 2002 ;
反应条件
bis(acetylacetonate)nickel(II); manganese; 2,9-dimethyl-1,10-phenanthroline in N,N-dimethyl acetamide T=20°C; 1 h;
参考文献
Shrestha, Ruja; Dorn, Stephanie C. M.; Weix, Daniel J.
Journal of the American Chemical Society, 2013 , vol. 135, # 2 p. 751 - 762
参考文献
Warner-Lambert Company
Patent: US5482960 A1, 1996 ;
US 5482960 A
反应条件
1.1: LiTMP / tetrahydrofuran / 0.67 h / -78 °C 1.2: 56 percent / tetrahydrofuran / -78 - 20 °C 2.1: 92 percent / hydrogen; potassium carbonate / Pd/C / ethanol / 3 h View Scheme
参考文献
Mattson, Ronald J.; Sloan, Charles P.; Lockhart, Christopher C.; Catt, John D.; Gao, Qi; Huang, Stella
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 8004 - 8007
反应条件
sulfuric acid; dihydrogen peroxide; iodine in ethanol; water T=70°C; 0.5 h;
参考文献
WO2009/7399 A1, ;
Page/Page column 67 ;
反应条件
1: NaH, CuI / hexamethylphosphoric acid triamide / 2 h / 90 - 95 °C 2: NaOH / H2O / 2 h / 80 - 90 °C View Scheme
参考文献
Chemistry Letters, , p. 193 - 194
反应条件
1: 99 percent / P-ph-phen*Pd(0), NaOAc / dimethylformamide; H2O / 12 h / 130 °C 2: H2 / 5percent Pd/C / ethanol / 8 h / 100 °C / 3040 Torr 3: 71 percent / NaOH, Br2 / H2O / 0.25 h / 70 - 80 °C View Scheme
参考文献
Zhuangyu, Zhang; Yi, Pan; Hongwen, Hu; Tsi-yu, Kao
Synthetic Communications, 1990 , vol. 20, # 22 p. 3563 - 3574
反应条件
CuO in N,N-dimethyl-formamide T=100°C;
参考文献
Tetrahedron Letters, , vol. 54, # 35 p. 4732 - 4734
反应条件
tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=25 - 150°C; Heck reaction; 0.0916667 h; Microwave irradiation;
参考文献
Tetrahedron Letters, , vol. 49, # 47 p. 6607 - 6609
