6-氯烟酰氯合成路线

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F. HOFFMANN-LA ROCHE AG; BROTHERTON-PLEISS, Christine; JAIME-FIGUEROA, Saul; LOPEZ-TAPIA, Francisco Javier; LOU, Yan; OWENS, Timothy D.
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110-91-8吗啉+

58757-38-36-氯烟酰氯

64614-49-9(6-氯-3-吡啶)-4-吗啉甲酮

参考文献

VERTEX PHARMACEUTICALS INCORPORATED
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WO 2004/046120 A2

58757-38-36-氯烟酰氯

6271-78-96-氯烟酰胺

参考文献

Wang, Qing Min; Sun, Hui Kai; Huang, Run Qiu
Heteroatom Chemistry, 2004 , vol. 15, # 1 p. 67 - 70

58757-38-36-氯烟酰氯+

108-59-8丙二酸二甲酯

55676-22-72-氯-5-乙酰基吡啶

参考文献

Hajduk; Gomtsyan; Didomenico; Cowart; Bayburt; Solomon; Severin; Smith; Walter; Holzman; Stewart; McGaraughty; Jarvis; Kowaluk; Fesik
Journal of Medicinal Chemistry, 2000 , vol. 43, # 25 p. 4781 - 4786

58757-38-36-氯烟酰氯

55676-22-72-氯-5-乙酰基吡啶

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Piotrowski, David W.
Synlett, 1999 , # 7 p. 1091 - 1093

58757-38-36-氯烟酰氯+

75-16-1甲基溴化镁

55676-22-72-氯-5-乙酰基吡啶

参考文献

Kagabu, Shinzo; Kiriyama, Kazuhisa; Nishiwaki, Hisashi; Kumamoto, Yuko; Tada, Toshiji; Nishimura, Keiichiro
Bioscience, biotechnology, and biochemistry, 2003 , vol. 67, # 5 p. 980 - 988

58757-38-36-氯烟酰氯+

67-68-5二甲基亚砜

55676-22-72-氯-5-乙酰基吡啶

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Zheng, Guo Zhu; Lee, Chih-Hung; Pratt, John K.; Perner, Richard J.; Jiang, Mei Qun; Gomtsyan, Arthur; Matulenko, Mark A.; Mao, Yui; Koenig, John R.; Kim, Ki H.; Muchmore, Steve; Yu, Haixia; Kohlhaas, Kathy; Alexander, Karen M.; McGaraughty, Steve; Chu, Katharine L.; Wismer, Carol T.; Mikusa, Joseph; Jarvis, Michael F.; Marsh, Kennan; Kowaluk, Elizabeth A.; Bhagwat, Shripad S.; Stewart, Andrew O.
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67-56-1甲醇+

58757-38-36-氯烟酰氯

73781-91-66-氯烟酸甲酯

参考文献

DOW AGROSCIENCES LLC; BREWSTER, William; DEMETER, David; ERICKSON, W.; LOWE, Christian; KLITTICH, Carla; NUGENT, Jaime; RIEDER, Brent; SIDDALL, Thomas; YAO, Chenglin; YERKES, Carla; ZHU, Yuanming
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58757-38-36-氯烟酰氯

159153-42-1

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Habermann, Joerg; Ley, Steven V.; Scott, James S.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 10 p. 1253 - 1255

58757-38-36-氯烟酰氯

342417-01-06-(4-甲基哌嗪-1-基)-4-(2-甲基苯基)烟酰胺

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Harrington, Peter J.; Johnston, Dave; Moorlag, Henk; Wong, Jim-Wah; Hodges, L. Mark; Harris, Les; McEwen, Gerald K.; Smallwood, Blair
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