N5-苄氧羰基-L-鸟氨酸甲酯盐酸盐合成路线 （共 5 条）
反应条件
thionyl chloride
18 h; Ambient temperature;
参考文献
Rosowsky, Andre; Forsch, Ronald A.; Bader, Henry; Freisheim, James H.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 4 p. 1447 - 1454
参考文献
Hoechst Aktiengesellschaft; Genetech, Inc.
Patent: US6218415 B1, 2001 ;
反应条件
hydrogenchloride in 1,4-dioxane
T=20°C; 2 h;
参考文献
Jain, Manish; Barthwal, Manoj Kumar; Haq, Wahajul; Katti, Seturam B.; Dikshit, Madhu
Chemical Biology and Drug Design, 2012 , vol. 79, # 4 p. 459 - 469
反应条件
1: sodium hydrogencarbonate / tetrahydrofuran; water / 2 h / 20 °C
2: acetic acid; hydrogen; palladium 10 on activated carbon / methanol / 20 °C
View Scheme
参考文献
Xie, Yuanchao; Huang, Bing; Yu, Kexiang; Shi, Fangyuan; Liu, Tianqi; Xu, Wenfang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 12 p. 3556 - 3560
反应条件
triethylamine; dicyclohexyl-carbodiimide
参考文献
Poddubnaya,N.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1966 , vol. 36, p. 219 - 224,228 - 232
