4-苄基-2-苯基-2-噁唑啉-5-酮合成路线 （共 38 条）
反应条件
water; oxonium T=25°C; different reaction conditions; solvent effect; Rate constantProduct distribution;
参考文献
Daffe, Viviane; Fastrez, Jacques
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , p. 783 - 788
反应条件
(i) iPr2NEt, (ii) aq. HCl, AcOH; Multistep reaction;
参考文献
Kuebel,B. et al.
Chemische Berichte, 1979 , vol. 112, p. 128 - 137
反应条件
potassium in tetrahydrofuran 4 h;
参考文献
Canadian Journal of Chemistry, , vol. 65, p. 1624 - 1630
反应条件
triethylamine; diethylazodicarboxylate in chloroform 1.) 0 deg C, 10 min, 2.) 18 h;
参考文献
Jones, John H.; Witty, Michael J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 858 - 864
反应条件
water in various solvent(s) T=50°C; 35 h;
参考文献
Journal of Organic Chemistry, , vol. 58, # 12 p. 3252 - 3258
反应条件
water T=25°C; 40 h; with lipase from Pseudomonas sp. (AK), phosphate buffer, pH: 7.6; other lipases; Product distribution;
参考文献
MacOvei, Cristian; Vicennati, Paola; Quinton, Julia; Nevers, Marie-Claire; Volland, Herve; Creminon, Christophe; Taran, Frederic
Chemical Communications, 2012 , vol. 48, # 37 p. 4411 - 4413
反应条件
in water T=25°C; 42 h; biosynthesis by porcine PL (Fermlipase); phosphate buffer, pH: 7.6; Yield given;
参考文献
Gu, Rui-Lin; Lee, Ik-Soo; Sih, Charles J.
Tetrahedron Letters, 1992 , vol. 33, # 15 p. 1953 - 1956
反应条件
1: 24 h / 20 - 40 °C
2: oxalic acid / 110 - 120 °C
3: conc. HCl / Heating
View Scheme
参考文献
Peet; Burkhart; Angelastro; Giroux; Mehdi; Bey; Kolb; Neises; Schirlin
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 394 - 407
反应条件
oxygen; palladium on activated charcoal in acetic anhydride; acetic acid
T=25°C; Yield given. Yields of byproduct given;
参考文献
Bates, Robert B.; Fletcher, Frederick A.; Janda, Kim D.; Miller, William A.
Journal of Organic Chemistry, 1984 , vol. 49, # 16 p. 3038
反应条件
potassium tert-butylate in dimethyl sulfoxide
T=0°C; 2 h;
参考文献
Suda, Kohji; Hino, Fumio; Yijima, Chino
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 2 p. 882 - 885
