7-氨基-4-三氟甲基-2-喹啉酮合成路线 （共 5 条）
反应条件
T=150°C; Conrad-Limpach synthesis; 20 h;
参考文献
Kathuria, Abha; Priya, Nivedita; Chand, Karam; Singh, Prabhjot; Gupta, Anjali; Jalal, Sarah; Gupta, Shilpi; Raj, Hanumantharao G.; Sharma, Sunil K.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 4 p. 1624 - 1638
反应条件
1: ethanol / Heating
2: 8.5 g / p-TsOH / ethanol / 8 h / Heating
View Scheme
参考文献
van Oeveren, Arjan; Pio, Barbara A.; Tegley, Christopher M.; Higuchi, Robert I.; Wu, Min; Jones, Todd K.; Marschke, Keith B.; Negro-Vilar, Andres; Zhi, Lin
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1523 - 1526
反应条件
in dimethyl sulfoxide
T=50 - 110°C; 4 h;
参考文献
Pillai, Shyamala; Kozlov, Maxim; Marras, Salvatore A.E.; Krasnoperov, Lev N.; Mustaev, Arkady
Journal of Fluorescence, 2012 , vol. 22, # 4 p. 1021 - 1032
反应条件
citric acid
2 h; Cooling with ice;
参考文献
Pillai, Shyamala; Kozlov, Maxim; Marras, Salvatore A.E.; Krasnoperov, Lev N.; Mustaev, Arkady
Journal of Fluorescence, 2012 , vol. 22, # 4 p. 1021 - 1032
反应条件
human recombinant caspase 3 in dimethyl sulfoxide
aq. bufferEnzymatic reaction; Kinetics; Reagent/catalyst;
参考文献
Reszka, Przemyslaw; Schulz, Riad; Methling, Karen; Lalk, Michael; Bednarski, Patrick J.
ChemMedChem, 2010 , vol. 5, # 1 p. 103 - 117
