2-(4-异丁基苯基)丙腈合成路线 （共 25 条）
反应条件
1: 76 percent / <bis(dimethylphosphino)propane>nickel(II) chloride / diethyl ether / Heating 2: 68 percent / tetrakis(tri-p-tolyl phosphite)nickel(0), tri-p-tolyl phosphite, ZnCl2 / toluene; various solvent(s) View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 25 p. 5370 - 5372
反应条件
[Ni0(1,5-cyclooctadiene)2]; C57H58O5P2 in methanol; toluene T=20°C; 5 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 5 p. 1576 - 1580
Angew. Chem., , vol. 125, # 5 p. 1617 - 1621,5
反应条件
1: 71 percent / POCl3, HN(iPr)2 / CH2Cl2 / a) 1 h, 0-5 degC, b) 1 h, r.t. 2: 92 percent / 575 - 600 °C / 0 - 0 Torr View Scheme
参考文献
Chemische Berichte, , vol. 124, p. 1667 - 1672
反应条件
1.1: n-butyllithium / hexane; cyclohexane; tetrahydrofuran / 4 h / 0 °C / |Inert atmosphere 1.2: 10 h / 20 °C / |Inert atmosphere 2.1: [Ni0(1,5-cyclooctadiene)2]; C57H58O5P2 / methanol; toluene / 5 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 5 p. 1576 - 1580
Angew. Chem., , vol. 125, # 5 p. 1617 - 1621,5
反应条件
aluminum oxide; Corundum(Al2O3) + 5wtpercent K2CO3 + 5wtpercent polyethyleneglycol (mol. weight 6000); potassium carbonate T=180°C;
参考文献
Tundo, Pietro; Trotta, Francesco; Moraglio, Giovanni
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1070 - 1071
参考文献
Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands, , vol. 115, # 4 p. 256 - 260
参考文献
Chemistry Letters, , p. 887 - 890
反应条件
1: 90 percent / aq.NH3 / 4 h / Ambient temperature 2: 60 percent / P2O5 View Scheme
参考文献
Archiv der Pharmazie, , vol. 316, # 9 p. 752 - 755
反应条件
T=600°C; flash pyrolysis;
参考文献
Angewandte Chemie, , vol. 103, # 8 p. 907 - 915
反应条件
lithium cyanide; ammonia; lithium 1) THF, 10 min, r.t., 2) THF, -78 deg C, 10 min; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 607 - 610
