反应条件
1: 1.) LiH, 2.) Li / 1.) THF, 4 h, 2.) THF, 17 h
2: 1.) NH2NH2*H2O, 2.) KO-t-Bu / 1.) ethanol, 7 h, heating, 2.) DMSO, 24 h, 80 deg C
3: 91 percent / BBr3 / CH2Cl2 / 1.) -80 deg C, 3 d, 2.) 72 h
4: 1.) LiNH2, Fe(NO3)3 / 1.) liq. NH3, THF, HMPA, 2.) liq. NH3, THF, HMPA, 40 deg C, 24 h
5: p-TsOH / ethanol / 3 h / Heating
6: 0.1704 g / PBr3 / CHCl3 / 16 h / -30 deg C to r. t.
7: 1.) EtMgBr, CuCl / 1.) THF, 1 h, 2.) THF, 72 h, 35 deg C
8: 50 percent / H2, quinoline / 5 percent Pd-BaSO4 / ethyl acetate / 2 h / Ambient temperature
View Scheme
参考文献
Caplin, Joseph; Tyman, John H. P.
Journal of Chemical Research, Miniprint, 1982 , # 2 p. 321 - 351
