反应条件
1: 90 percent / N,N'-dicyclohexylcarbodiimide (DCCI) / tetrahydrofuran / Ambient temperature 2: 1.) NH3, 2.) AcOH / 1.) CHCl3, 5 min, 2.) THF, 24 h 3: 98 percent / 4 M HCl / dioxane / 0.75 h 4: 1.) NH3, 2.) AcOH / 1.) CHCl3, 5 min, 2.) THF, 24 h 5: 91 percent / 2 M HCl / acetic acid / 0.75 h 6: 1.) NH3, 2.) AcOH / 1.) CHCl3, 5 min, 2.) DMF, THF, 24 h 7: 1.) 2 M NaOH, 2.) 2M HCl / 1.) methanol, water, 4 h, 2.) AcOH, 45 min View Scheme
参考文献
Polish Journal of Chemistry, , vol. 55, # 3 p. 573 - 582
