N-(叔丁氧基羰基)-L-缬氨酸甲酯合成路线 （共 63 条）
反应条件
sodium hydrogencarbonate in tetrahydrofuran; methanol T=20°C; 20 h;
参考文献
Chemistry - A European Journal, , vol. 11, # 1 p. 69 - 80
反应条件
in dichloromethane T=0 - 20°C;
参考文献
Chemical Communications, , vol. 50, # 13 p. 1588 - 1590
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=0 - 20°C;
参考文献
Chemical Communications, , vol. 46, # 17 p. 2947 - 2949
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate T=20°C; Hydrogenation; 3 h;
参考文献
Journal of Organic Chemistry, , vol. 64, # 20 p. 7670 - 7674
反应条件
triethylsilane; palladium on activated charcoal in methanol 0.833333 h;
参考文献
Journal of Organic Chemistry, , vol. 72, # 17 p. 6599 - 6601
反应条件
4-methyl-morpholine in ethyl acetate
参考文献
Journal of the American Chemical Society, , vol. 102, # 23 p. 7044 - 7047
反应条件
in ethylene glycol dimethyl ether T=20°C;
参考文献
Organic Letters, , vol. 4, # 4 p. 585 - 587
Tetrahedron, , vol. 62, # 50 p. 11599 - 11607
反应条件
1: (2S,5S)-5-isopropyl-3,6-dimethoxy-2-(1-methyldeca-2,3-dien-4-yl)-2,5-dihydropyrazine With water; trifluoroacetic acid in tetrahydrofuran T=20°C; 2: di-tert-butyl dicarbonate With triethylamine in dichloromethane T=20°C; 12 h; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 21 p. 3605 - 3612
反应条件
in dichloromethane T=25°C; 4 h; Inert atmosphere;
参考文献
Chemical Communications, , vol. 46, # 24 p. 4405 - 4407
反应条件
1: (2R,5S)-5-isopropyl-3,6-dimethoxy-2-(nona-1,2-dien-3-yl)-2,5-dihydropyrazine With water; trifluoroacetic acid in tetrahydrofuran T=20°C; 2: di-tert-butyl dicarbonate With triethylamine in dichloromethane T=20°C; 12 h; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 21 p. 3605 - 3612
