(S)-(+)-2-氨基-1-丁醇合成路线 （共 20 条）
反应条件
hydrogen; palladium on activated charcoal in methanol P=112509 Torr; 72 h;
参考文献
Segat-Dioury, Fabienne; Lingibe, Olivier; Graffe, Bernadette; Sacquet, Marie-Claude; Lhommet, Gerard
Tetrahedron, 2000 , vol. 56, # 2 p. 233 - 248
反应条件
ethylenediamine in ethanol deprotection; 18 h; Heating;
参考文献
Trost, Barry M.; Bunt, Richard C.; Lemoine, Remy C.; Calkins, Trevor L.
Journal of the American Chemical Society, 2000 , vol. 122, # 25 p. 5968 - 5976
反应条件
penicillin G acylase; Eupergit C in water T=30°C; Hydrolysis; pH=7.8; 0.583333 h; Enzymatic reaction;
参考文献
Fadnavis; Sharfuddin, Mohd.; Vadivel
Tetrahedron Asymmetry, 1999 , vol. 10, # 23 p. 4495 - 4500
反应条件
1: With (2R,3S)-(-)-di-O-benzoyl tartaric acid in acetone T=25°C; 6 h; 2: With potassium hydroxide in dichloromethane
参考文献
Periasamy, Mariappan; Sivakumar, Sangarappan; Reddy, Meda Narsi
Synthesis, 2003 , # 13 p. 1965 - 1967
反应条件
hydrogen; acetic acid; palladium on activated charcoal in methanol 24 h; Ambient temperature;
参考文献
Koh; Ben; Durst
Tetrahedron Letters, 1993 , vol. 34, # 28 p. 4473 - 4476
反应条件
hydrogen; nickel; acetic acid in methanol P=9000.72 Torr; 24 h;
参考文献
Kotkar, Shriram P.; Sudalai, Arumugam
Tetrahedron Asymmetry, 2006 , vol. 17, # 11 p. 1738 - 1742
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Purification / work up;
参考文献
WO2010/148191 A2, ;
Page/Page column 45-49; 59 ;
反应条件
tetrahydrofuran; lithium aluminium tetrahydride
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 16, p. 71,77
反应条件
1: T=140°C; Acylation; 24 h; 2: With penicillin G acylase; Eupergit C in water T=30°C; Hydrolysis; pH=7.8; 0.583333 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 10, # 23 p. 4495 - 4500
反应条件
sodium hydroxide T=80°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 23 p. 5079 - 5082
