2-甲基-4H-吡喃-4-酮合成路线 （共 6 条）
反应条件
trifluoroacetic acid in benzene
Ambient temperature12-18 h;
参考文献
Koreeda, Masato; Akagi, Hiroshi
Tetrahedron Letters, 1980 , vol. 21, p. 1197 - 1200
反应条件
in various solvent(s)
T=170°C; Yield given;
参考文献
Zawacki, Frank J.; Crimmins, Michael T.
Tetrahedron Letters, 1996 , vol. 37, # 36 p. 6499 - 6502
反应条件
1: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 30 min, 2.) gradually warmed to room temp., 2-3 h, room temp.
2: 85 percent / trifluoroacetic acid / benzene / Ambient temperature; 12-18 h
View Scheme
参考文献
Koreeda, Masato; Akagi, Hiroshi
Tetrahedron Letters, 1980 , vol. 21, p. 1197 - 1200
参考文献
Sato, Masayuki; Ogasawara, Hiromischi; Kato, Keiko; Sakai, Masako; Kato, Tetsuzo
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4300 - 4305
参考文献
Bell, Kelcey; Sadasivam, Dhandapani V.; Gudipati, Indra Reddy; Ji, Hua; Birney, David
Tetrahedron Letters, 2009 , vol. 50, # 12 p. 1295 - 1297
反应条件
vinyl 1-butyl ether; toluene-4-sulfonic acid
multistep reaction: 1.) benzene, 2 h, reflux, 2.) 4:1 THF/water, reflux; reactions of derivatives; Product distribution;
参考文献
Zawacki, Frank J.; Crimmins, Michael T.
Tetrahedron Letters, 1996 , vol. 37, # 36 p. 6499 - 6502
