3-苄氧基-4-甲氧基苯甲酸合成路线 （共 13 条）
反应条件
sodium chlorite; aminosulfonic acid; acetic acid in water T=20°C; 1 h;
参考文献
Wang, Min; Gao, Mingzhang; Mock, Bruce H.; Miller, Kathy D.; Sledge, George W.; Hutchins, Gary D.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 24 p. 8599 - 8607
参考文献
Journal of the Chemical Society, , p. 817,818
反应条件
1: With tetrabutyl-ammonium chloride; potassium carbonate in water; toluene T=80°C; 2 h; 2: With water; sodium hydroxide in methanol; toluene 2 h; Reflux;
参考文献
OTSUKA PHARMACEUTICAL CO., LTD.; OKADA, Minoru; KABUKI, Takashi; FUJIEDA, Shigeo; KOSEKI, Nao
Patent: WO2014/34958 A1, 2014 ;
Location in patent: Page/Page column 59-60 ;
反应条件
1: 94 percent / K2CO3; KI / dimethylformamide / 22 h / 65 °C 2: 93 percent / sodium chlorite; sulfamic acid; acetic acid / H2O / 1 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 24 p. 8599 - 8607
反应条件
1: potassium carbonate / acetone / 12 h / Inert atmosphere; Reflux 2: sodium dihydrogenphosphate; sodium chlorite; dihydrogen peroxide / water; acetonitrile / 0 - 10 °C View Scheme
参考文献
ACS Medicinal Chemistry Letters, , vol. 3, # 4 p. 317 - 321
反应条件
1: methanol. KOH-solution 2: aqueous KOH-solution View Scheme
参考文献
Journal of the Chemical Society, , p. 817,818
反应条件
1: aqueous hydrobromic acid 2: hydrogen chloride 3: methanol. KOH-solution 4: aqueous KOH-solution View Scheme
参考文献
Journal of the Chemical Society, , p. 817,818
反应条件
1: diethyl ether; thionyl chloride; pyridine 2: sodium-<3-benzyloxy-4-methoxy benzoate> / 190 °C / Erwaermen des Reaktionsprodukts mit wss.-aethanol. Kalilauge 3: acetic acid; aqueous hydrochloric acid View Scheme
参考文献
Lovecy; Robinson; Sugasawa
Journal of the Chemical Society, 1930 , p. 817,818
反应条件
1: 1.72 g / 3 h / 130 - 140 °C
2: K2CO3 / 4 h / 130 - 140 °C
3: 0.66 g / PPA / 1 h / 115 - 125 °C
4: 1.) LiAlH4; 2.) HCl / 1.) THF, heating, 6 h; 2.) EtOH, hearing, 2 h
View Scheme
参考文献
Masood, M.; Tiwari, K. P.
Acta Chimica Hungarica, 1983 , vol. 113, # 2 p. 177 - 182
