5-苯基噁唑烷-2,4-二酮合成路线 （共 29 条）
反应条件
triethylamine in tetrahydrofuran T=0 - 5°C; 1 h;
参考文献
Schnur; Morville
Journal of Medicinal Chemistry, 1986 , vol. 29, # 5 p. 770 - 778
反应条件
sodium in methanol 3 h; Reflux;
参考文献
Santana, Ana Bela; Lucas, Susana D.; Goncalves, Lidia M.; Correia, Henrique F.; Cardote, Teresa A.F.; Guedes, Rita C.; Iley, Jim; Moreira, Rui
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 3993 - 3997
反应条件
phosphate buffer (pH=8-9) in water T=40°C; 12 h;
参考文献
Stadlbauer, Wolfgang; Kappe, Thomas
Monatshefte fuer Chemie, 1985 , vol. 116, p. 1005 - 1016
反应条件
sodium hydroxide; potassium dihydrogenphosphate; dihydrogen peroxide in water T=40 - 50°C; 12 h;
参考文献
Stadlbauer, Wolfgang; Kappe, Thomas
Monatshefte fuer Chemie, 1985 , vol. 116, p. 1005 - 1016
反应条件
sodium ethanolate; sodium hydride in ethanol T=0°C; 2.5 h; Reflux;
参考文献
Dhanawat, Meenakshi; Banerjee, Anupam G.; Shrivastava, S. K.
Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 2807 - 2822,16
反应条件
sulfuric acid 0.5 h; Heating;
参考文献
Kus, Piotr; Jones, Peter G.; Celinski, Rafal
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2005 , vol. 60, # 8 p. 853 - 857
参考文献
Journal of the American Chemical Society, , vol. 67, p. 522
US2338220 , ;
反应条件
1: 89 percent / HCl / 16 h / 5 °C 2: 67 percent / Et3N / tetrahydrofuran / 1 h / 0 - 5 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 5 p. 770 - 778
反应条件
1: ZnI2 / CH2Cl2 / 65 h / Ambient temperature 2: 89 percent / HCl / 16 h / 5 °C 3: 67 percent / Et3N / tetrahydrofuran / 1 h / 0 - 5 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 5 p. 770 - 778
参考文献
Journal of the American Chemical Society, , vol. 61, p. 3491
