2-(吲哚甲基)四氢呋喃合成路线 (共 18 条)
反应条件
acetone; sodium iodide
参考文献
Gilman; Brown
Iowa State College Journal of Science, 1931 , vol. 6, p. 11,13
反应条件
in 1,2-dichloro-ethane
T=25°C; also in the presence of adamantylideneadamoratane and 1-pentanol; Rate constant;
参考文献
Neverov, Alexei A.; Muise, Theresa L.; Brown
Canadian Journal of Chemistry, 1997 , vol. 75, # 12 p. 1844 - 1850
反应条件
acetic acid; iron(II) chloride in water
2 h; Heatingcompare with other reagents; Product distribution;
参考文献
Taillez, Bernard; Bertrand, Michele Paula; Surzur, Jean-Marie
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , p. 547 - 554
反应条件
1: 73 percent / tetrahydrofuran; hexamethylphosphoric acid triamide
2: 84 percent / 6percent sodium amalgam, Na2HPO4 buffer / methanol; tetrahydrofuran / -20 °C
View Scheme
参考文献
Carr, Richard V. C.; Paquette, Leo A.
Journal of the American Chemical Society, 1980 , vol. 102, # 2 p. 853 - 855
反应条件
1: 76 percent / NaH / dimethylformamide
2: 6 percent Na-Hg, Na2HPO4 / methanol / 0.5 h / Ambient temperature
View Scheme
参考文献
Paquette, Leo A.; Kinney, William A.
Tetrahedron Letters, 1982 , vol. 23, # 2 p. 131 - 134
反应条件
1: 76 percent / NaH / dimethylformamide
2: 6 percent Na-Hg, Na2HPO4 / methanol / 0.5 h / Ambient temperature
View Scheme
参考文献
Paquette, Leo A.; Kinney, William A.
Tetrahedron Letters, 1982 , vol. 23, # 2 p. 131 - 134
反应条件
1: 76 percent / NaH / dimethylformamide
2: 1.) 6percent Na/Hg, Na2HPO4, 2.) p-toluenesulfonic acid / 1.) methanol, room temp., 30 min, 2.) ethanol, reflux, 20 h
View Scheme
参考文献
Paquette, Leo A.; Kinney, William A.
Tetrahedron Letters, 1982 , vol. 23, # 2 p. 131 - 134
反应条件
1: 76 percent / NaH / dimethylformamide
2: 1.) 6percent Na/Hg, Na2HPO4, 2.) p-toluenesulfonic acid / 1.) methanol, room temp., 30 min, 2.) ethanol, reflux, 20 h
View Scheme
参考文献
Paquette, Leo A.; Kinney, William A.
Tetrahedron Letters, 1982 , vol. 23, # 2 p. 131 - 134