2-(2-噻吩基)-1,3-二氧戊环合成路线 （共 8 条）
反应条件
toluene-4-sulfonic acid in benzene 16 h; Heating;
参考文献
Carpenter, Andrew J,; Chadwick, Derek J.
Tetrahedron, 1985 , vol. 41, # 18 p. 3803 - 3812
反应条件
potassium tert-butylate in tetrahydrofuran; N,N-dimethyl-formamide T=-60°C; 1.5 h;
参考文献
Barbasiewicz, Michal; Makosza, Mieczyslaw
Organic Letters, 2006 , vol. 8, # 17 p. 3745 - 3748
反应条件
1: 2-(α-thienyl)-1,3-dioxolane With n-butyllithium in tetrahydrofuran T=-78°C; 2: carbon dioxide With sulfuric acid in tetrahydrofuran; water
参考文献
Mahboobi, Siavosh; Dove, Stefan; Sellmer, Andreas; Winkler, Matthias; Eichhorn, Emerich; Pongratz, Herwig; Ciossek, Thomas; Baer, Thomas; Maier, Thomas; Beckers, Thomas
Journal of Medicinal Chemistry, 2009 , vol. 52, # 8 p. 2265 - 2279
反应条件
carbon tetrabromide in water; acetonitrile T=45°C; 2 h; sonication;
参考文献
Lee, Adam S.-Y.; Cheng
Tetrahedron, 1997 , vol. 53, # 42 p. 14255 - 14262
反应条件
n-butyllithium in tetrahydrofuran; hexane
参考文献
American Home Products Corporation
Patent: US2002/26052 A1, 2002 ;
反应条件
n-butyllithium in tetrahydrofuran T=-78 - 25°C;
参考文献
Yeh-Yung Lin, Ryan; Wu, Feng-Ling; Chang, Chia-Hao; Chou, Hsien-Hsin; Chuang, Tzu-Man; Chu, Te-Chun; Hsu, Chih-Yu; Chen, Ping-Wei; Ho, Kuo-Chuan; Lo, Yih-Hsing; Lin, Jiann T.
Journal of Materials Chemistry A, 2014 , vol. 2, # 9 p. 3092 - 3101
参考文献
Gol'dfarb; Konstantinow
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1959 , p. 121,127; engl. Ausg. S. 108, 113
engl. Ausg., S. 108, 113
参考文献
Gol'dfarb; Konstantinow
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1959 , p. 121,127; engl. Ausg. S. 108, 113
engl. Ausg., S. 108, 113
