1-氨基-1,2,3,4-四氢喹啉合成路线 (共 6 条)
反应条件
titanium tetrachloride; magnesium in diethyl ether; 1,2-dichloro-ethane 0.5 h; Ambient temperature;
参考文献
Landriani; Barlocco; Pinna; Demontis; Miele; Enrico; Anania
Farmaco, 1989 , vol. 44, # 11 p. 1059 - 1068
反应条件
O-(2,4,6-trimethylbenzenesulfonyl)hydroxylamine in dichloromethane T=25°C; 1 h; Yield given;
参考文献
European Journal of Medicinal Chemistry, , vol. 21, # 3 p. 181 - 185
反应条件
1: 94 percent / NaNO3 / H2O; acetic acid / 2 h / Ambient temperature 2: 92 percent / TiCl4, Mg / 1,2-dichloro-ethane; diethyl ether / 0.5 h / Ambient temperature View Scheme
参考文献
Farmaco, , vol. 44, # 11 p. 1059 - 1068
反应条件
T=195 - 200°C; 0.5 h;
参考文献
Viswanathan, V.; Kaul, C. L.; Grewal, R. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 9 p. 776 - 779
反应条件
1: 92 percent / ethanol / 12 h / Heating 2: PPA / 0.08 h / 150 °C View Scheme
参考文献
Benincori, Tiziana; Pagani, Silvia Bradamante; Fusco, Raffaello; Sannicolo, Franco
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2721 - 2728
反应条件
in ethanol
12 h; Heating;
参考文献
Benincori, Tiziana; Pagani, Silvia Bradamante; Fusco, Raffaello; Sannicolo, Franco
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2721 - 2728