2,4-二氧代-4-(对甲苯)丁酸乙酯合成路线 （共 6 条）
反应条件
hydroxylamine hydrochloride in ethanol 1 h; Heating;
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392
反应条件
1: NH2OH*HCl / ethanol / 1 h / Heating 2: LiAlH4 / diethyl ether / 0.5 h / 40 °C View Scheme
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392
反应条件
1: NH2OH*HCl / ethanol / 1 h / Heating 2: LiAlH4 / diethyl ether / 0.5 h / 40 °C 3: PCC / CH2Cl2 / 5 h / 20 °C View Scheme
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392
反应条件
sodium ethanolate in ethanol
T=0 - 20°C;
参考文献
Kraem, Jihene Ben; Amri, Hassen
Synthetic Communications, 2013 , vol. 43, # 1 p. 110 - 117
反应条件
1: 2.) NaOH / 1.) water, reflux, 5 min, room temp., 2 h; 2.) water, reflux, 15 min
2: 70 percent / phosphorus pentasulfide / pyridine / Heating
3: 1.) sodium methoxide; / 1.) methanol; 2.) room temp., overnight
View Scheme
参考文献
Ibrahim, Yehia A.; Abdel-Hady, S. A. L.; Badawy, M. A.; Ghazala, M. A. H.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 913 - 915
反应条件
1: 2.) NaOH / 1.) water, reflux, 5 min, room temp., 2 h; 2.) water, reflux, 15 min
2: 70 percent / phosphorus pentasulfide / pyridine / Heating
View Scheme
参考文献
Eid, M. M.; Badawy, M. A.; Ghazala, M. A. H.; Ibrahim, Yehia A.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1709 - 1711
