1-羟基喹啉-2(1H)-酮合成路线 （共 40 条）
反应条件
1: 69 percent / conc. HCl, H2 / 5percent Pt/C sulfided / methanol; H2O / 2699.3 Torr / 1-2 h
2: 83 percent / Na2CO3 / H2O / 6 h / Heating
View Scheme
参考文献
McCord; DuBose; Shafer; Davis
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 643 - 646
反应条件
1: 1) NaNO2, conc.HCl, 2) CuCl / 1) acetone-water, below 8 deg C
2: 69 percent / conc. HCl, H2 / 5percent Pt/C sulfided / methanol; H2O / 2699.3 Torr / 1-2 h
3: 83 percent / Na2CO3 / H2O / 6 h / Heating
View Scheme
参考文献
McCord; DuBose; Shafer; Davis
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 643 - 646
反应条件
sodium hydroxide in tetrahydrofuran
2 h; Ambient temperature; Product distribution;
参考文献
Tagawa, Yoshinobu; Honjo, Noriko; Goto, Yoshinobu
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 564 - 571
反应条件
hydrogenchloride; ethanol; water
参考文献
Newbold; Spring
Journal of the Chemical Society, 1948 , p. 1864
反应条件
sodium hydroxide; p-toluenesulfonyl chloride
Ambient temperature;
参考文献
Tagawa, Yoshinobu; Honjo, Noriko; Goto, Yoshinobu; Chiba, Takuo; Kato, Tetsuzo
Heterocycles, 1983 , vol. 20, # 1 p. 161
反应条件
1: hydrogen peroxide; water; acetic acid
2: water; ethanol; hydrochloric acid
View Scheme
参考文献
Newbold; Spring
Journal of the Chemical Society, 1948 , p. 1864
参考文献
Friedlaender; Ostermaier
Chemische Berichte, 1881 , vol. 14, p. 1920
Chemische Berichte, 1882 , vol. 15, p. 332
反应条件
sodium hydroxide in tetrahydrofuran
2 h; Ambient temperaturedifferent reactant ratios; Product distributionMechanism;
参考文献
Tagawa, Yoshinobu; Honjo, Noriko; Goto, Yoshinobu
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 2 p. 564 - 571
反应条件
hydrogen; platinum on activated charcoal in ethanol
P=2699.3 Torr; 2 h;
参考文献
McCord; DuBose; Shafer; Davis
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 643 - 646
反应条件
1: triethylamine / dichloromethane / 12 h / 20 °C
2: water; methanol / |UV-irradiation; |Photolysis
View Scheme
参考文献
Ikbal, Mohammed; Banerjee, Rakesh; Atta, Sanghamitra; Jana, Avijit; Dhara, Dibakar; Anoop, Anakuthil; Singh, N. D. Pradeep
Chemistry - A European Journal, 2012 , vol. 18, # 38 p. 11968 - 11975
