2-氨基-5-溴苯甲酸合成路线 （共 139 条）
反应条件
1: With water; sodium hydroxide in tetrahydrofuran; ethanol T=20°C; 12 h; 2: With hydrogenchloride in water pH=4;
参考文献
TIBOTEC PHARMACEUTICALS; VANDYCK, Koen; VERSCHUEREN, Wim Gaston; RABOISSON, Pierre Jean-Marie Bernard
Patent: WO2012/13643 A1, 2012 ;
Location in patent: Page/Page column 43 ;
反应条件
1-butyl-3-methylimidazolium tribromide T=25°C; 0.666667 h;
参考文献
Bagmanov
Russian Journal of Applied Chemistry, 2009 , vol. 82, # 9 p. 1570 - 1576
反应条件
polymer-supported formate; magnesium in methanol T=20°C; 2.5 h;
参考文献
Abiraj, Keelara; Srinivasa, Gejjalagere R.; Gowda, D. Channe
Australian Journal of Chemistry, 2005 , vol. 58, # 2 p. 149 - 151
反应条件
1: With sodium N-bromobenzenesulfonamide; sodium hydroxide; palladium dichloride in water; acetonitrile T=60°C; pH=12; 3.66667 h; 2: in water Acidic conditions;
参考文献
Karthikeyan; Jagadeesh, Rajenahally V.; Sree Sandhya; Puttaswamy; Nithya; Kumar, S. Senthil; Bhagat
Applied Organometallic Chemistry, 2011 , vol. 25, # 1 p. 34 - 46
反应条件
1: With sodium N-bromobenzenesulfonamide; sodium hydroxide; palladium dichloride in water; acetonitrile T=60°C; pH=12; 3.66667 h; 2: in water Acidic conditions;
参考文献
Kumar, C. Vinod; Shivananda; Raju, C. Nagu; Jagadeesh
Synthetic Communications, 2010 , vol. 40, # 23 p. 3480 - 3487
反应条件
N-bromosuccinmide T=25°C; Solid phase reaction; bromination; 0.025 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 2, , # 6 p. 1113 - 1118
反应条件
potassium permanganate; water Verseifen des Produkts mit konz. Salzsaeure;
参考文献
Journal of the American Chemical Society, , vol. 27, p. 1480
Chemische Berichte, , vol. 22, p. 1645
反应条件
water; sodium hydroxide 4 h; Reflux;
参考文献
Boettcher, Stephan; Thiem, Joachim
European Journal of Organic Chemistry, 2014 , vol. 2014, # 3 p. 564 - 574
反应条件
sodium hypochlorite; sodium hydroxide in water T=1 - 78°C; Hofmann degradation;
参考文献
Molecules, , vol. 15, # 8 p. 5561 - 5580
反应条件
anthranilic acid in benzene 6 h; Heating;
参考文献
Monatshefte fur Chemie, , vol. 127, # 1 p. 103 - 110
