N-乙酰-N-苯基甘氨酸合成路线 （共 16 条）
反应条件
aluminium trichloride
参考文献
BASF
Patent: DE188436 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 9, p. 514
参考文献
B.A.S.F.
Patent: DE188436 ;
反应条件
(NH4)2S2O8; silver nitrate in water; acetonitrile T=80 - 90°C; 0.666667 h;
参考文献
Heterocycles, , vol. 34, # 2 p. 357 - 362
反应条件
(NH4)2S2O8; silver nitrate in water; acetonitrile T=80 - 90°C; 0.666667 h;
参考文献
Tada, Masaru; Furuse, Reiko; Kashima, Hiroko
Heterocycles, 1992 , vol. 34, # 2 p. 357 - 362
反应条件
1: With lithium hydroxide; water in tetrahydrofuran; methanol; water
T=20°C;
2: With hydrogenchloride in water
pH=1;
参考文献
Dolle, Roland E.; Chu, Guo-Hua; Gu, Minghua
Patent: US2005/107355 A1, 2005 ;
Location in patent: Page/Page column 30 ;
反应条件
1-methyl-pyrrolidin-2-one; sulfuric acid; lithium bromide; palladium on activated charcoal
T=130°C; P=45003.6 Torr; 60 h;
参考文献
Beller, Matthias; Moradi, Wahed A.; Eckert, Markus; Neumann, Helfried
Tetrahedron Letters, 1999 , vol. 40, # 24 p. 4523 - 4526
反应条件
sodium hydroxide in ethanol; water
Heating;
参考文献
DeRuiter, Jack; Swearingen, Blake E.; Wandrekar, Vinay; Mayfield, Charles A.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 1033 - 1038
反应条件
1: 1) NaH / 1) DMF, 60-70 deg C, 1 h, 2) 80 deg C, overnight
2: NaOH / ethanol; H2O / Heating
View Scheme
参考文献
DeRuiter, Jack; Swearingen, Blake E.; Wandrekar, Vinay; Mayfield, Charles A.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 5 p. 1033 - 1038
参考文献
Bischoff; Hausdoerfer
Chemische Berichte, 1892 , vol. 25, p. 2288
Chemische Berichte, 1890 , vol. 23, p. 1998
反应条件
1: diethyl ether; water
2: benzene
View Scheme
参考文献
Rebuffat
Gazzetta Chimica Italiana, 1887 , vol. 17, p. 234
Gazzetta Chimica Italiana, 1890 , vol. 20, p. 122
