N-(4-羟基苯基)-N-甲基乙酰胺合成路线 （共 13 条）
反应条件
1: nickel; ethanol / 180 °C / Hydrogenation 2: aqueous sulfuric acid View Scheme
参考文献
CIBA
Patent: US2152960 , 1936 ;
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / Inert atmosphere 2: [Ni0(1,5-cyclooctadiene)2]; methyl dimethoxy silane; tri-cyclo-hexyl-phosphine / toluene / 12 h / 80 °C / Inert atmosphere View Scheme
参考文献
Tobisu, Mamoru; Yamakawa, Ken; Shimasaki, Toshiaki; Chatani, Naoto
Chemical Communications, 2011 , vol. 47, # 10 p. 2946 - 2948
反应条件
1: sulfuric acid / und Aufbewahren des Reaktionsgemisches bei 25grad
2: diluted NaOH-solution
View Scheme
参考文献
Meldola; Hollely
Journal of the Chemical Society, 1914 , vol. 105, p. 2076
反应条件
water
T=5°C; 0.0166667 h;
参考文献
Fernando; Calder; Ham
Journal of Medicinal Chemistry, 1980 , vol. 23, # 11 p. 1153 - 1158
反应条件
in water
0.0333333 h; Heating;
参考文献
Harvison, Peter J.; Forte, Anthony J.; Nelson, Sidney D.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1737 - 1743
反应条件
water; sodium acetate
参考文献
Jacobs; Heidelberger
Journal of the American Chemical Society, 1917 , vol. 39, p. 2190
反应条件
lead(IV) acetate in trifluoroacetic acid
1 h ice cooling, 3.6 h;
参考文献
Taniguchi, Mikio; Anjiki, Tomiko; Nakagawa, Masako; Hino, Tohru
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 7 p. 2544 - 2554
参考文献
Meldola; Hollely
Journal of the Chemical Society, 1914 , vol. 105, p. 2076
参考文献
Hoechster Farbw.
Patent: DE89595 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, 4,1165.1181
参考文献
Hoechster Farbw.
Patent: DE79098 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, 4,1165.1181
