1: 3-iodoprop-1-ene With chromium dichloride; H2Salen; triethylamine in acetonitrile T=20°C; Metallation; 2: benzaldehyde With chloro-trimethyl-silane in acetonitrile Addition;
参考文献
Angewandte Chemie - International Edition, , vol. 38, # 22 p. 3357 - 3359
1: n-butyl-magnesium chloride With titanium(IV) isopropylate in dichloromethane T=-78°C; 0.166667 h; Inert atmosphere; 2: benzaldehyde With (R)-3-(3,5-diphenylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl in diethyl ether; dichloromethane T=0°C; 3 h; Inert atmosphere; 3: With hydrogenchloride; water in diethyl ether; dichloromethane T=0°C; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 83, # 1 p. 19 - 32
1: 3-chloroprop-1-ene With chromium dichloride; H2Salen; triethylamine in acetonitrile T=20°C; Metallation; 2: benzaldehyde With chloro-trimethyl-silane in acetonitrile Addition;
参考文献
Angewandte Chemie - International Edition, , vol. 38, # 22 p. 3357 - 3359
2,2-dimethyl-1-propanenitrile; titanium(III) chloride; copper in dichloromethane T=0°C; Reformatsky reaction; 12 h; Title compound not separated from byproducts;
