咪唑并[1,2-a]吡啶-2-乙腈合成路线 (共 3 条)
反应条件
sodium cyanide in ethanol; water
参考文献
Abbott Laboratories; Abbott GmbH and Co. KG
Patent: US2013/5705 A1, 2013 ;
US 20130005705 A1
反应条件
1: 2-(bromomethyl)-1H-imidazo[1,2-a]pyridinium bromide With sodium hydrogencarbonate in methanol; water
0.0833333 h;
2: potassium cyanide in methanol; water
6 h; Further stages.;
参考文献
Kutrov; Kovalenko; Volovenko
Russian Journal of Organic Chemistry, 2008 , vol. 44, # 2 p. 257 - 262
反应条件
1: sodium hydrogencarbonate / ethylene glycol dimethyl ether; ethanol; water
2: sodium cyanide / ethanol; water
View Scheme
参考文献
Abbott Laboratories; Abbott GmbH and Co. KG
Patent: US2013/5705 A1, 2013 ;
US 20130005705 A1