N-Boc-4-乙基-4-哌啶甲酸甲酯合成路线 （共 4 条）
反应条件
lithium diisopropyl amide in tetrahydrofuran T=-78°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 13 p. 2167 - 2172
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 14 p. 3675 - 3678
反应条件
potassium hydroxide in methanol Heating;
参考文献
Jiang, Xiao-Hua; Song, Yan-Li; Long, Ya-Qiu
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 14 p. 3675 - 3678
反应条件
1: KOH / methanol / Heating
2: NMM / tetrahydrofuran / 1 h / -15 °C
3: aq. NaN3 / tetrahydrofuran / -15 - 20 °C
4: toluene / 1.5 h / 90 °C
5: aq. KOH / tetrahydrofuran / 0 °C
View Scheme
参考文献
Jiang, Xiao-Hua; Song, Yan-Li; Long, Ya-Qiu
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 14 p. 3675 - 3678
反应条件
1: LAH / tetrahydrofuran / 20 °C
2: SO3*Py; NEt3 / dimethylsulfoxide / 20 °C
View Scheme
参考文献
Ogino, Yoshio; Ohtake, Norikazu; Kobayashi, Kensuke; Kimura, Toshifumi; Fujikawa, Toru; Hasegawa, Takuro; Noguchi, Kazuhito; Mase, Toshiaki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 13 p. 2167 - 2172
