11H-吡啶并[2,1-b]喹唑啉-11-酮合成路线 （共 24 条）
反应条件
1: 92 percent 2: 90 percent / aq. acetic acid / 3 h / -5 °C 3: 92 percent / PPA / 0.5 h / 180 °C View Scheme
参考文献
Koekoesi, Jozsef; Hermecz, Istvan; Szasz, Gyoergy; Meszaros, Zoltan
Tetrahedron Letters, 1981 , vol. 22, # 48 p. 4861 - 4862
参考文献
Seide
Justus Liebigs Annalen der Chemie, 1924 , vol. 440, p. 321
参考文献
Seide
Justus Liebigs Annalen der Chemie, 1924 , vol. 440, p. 321
反应条件
1: in N,N-dimethyl-formamide
T=85°C; 6 h;
2: With copper(l) iodide; caesium carbonate; L-proline in N,N-dimethyl-formamide
T=80 - 85°C; 6 h;
参考文献
Maity, Arindam; Mondal, Shyamal; Paira, Rupankar; Hazra, Abhijit; Naskar, Subhendu; Sahu, Krishnendu B.; Saha, Pritam; Banerjee, Sukdeb; Mondal, Nirup B.
Tetrahedron Letters, 2011 , vol. 52, # 23 p. 3033 - 3037
反应条件
dipotassium peroxodisulfate; palladium diacetate in trifluoroacetic acid
T=70°C; P=760.051 Torr; 4 h; Schlenk technique; Reagent/catalystSolvent;
参考文献
Liang, Dongdong; He, Yimiao; Zhu, Qiang
Organic Letters, 2014 , vol. 16, # 10 p. 2748 - 2751
反应条件
pyridine; oxygen; cupric trifluoroacetate in N,N-dimethyl-formamide
T=130°C; P=760.051 Torr; 48 h; Schlenk technique;
参考文献
Yu, Jipan; Yang, Haijun; Jiang, Yuyang; Fu, Hua
Chemistry - A European Journal, 2013 , vol. 19, # 13 p. 4271 - 4277
反应条件
anhydrous copper sulphate; potassium carbonate; N,N-dimethyl-formamide
0.0666667 h; microwave irradiation;
参考文献
Pellon, Rolando F.; Martin, Ana; Docampo, Maite L.; Mesa, Miriam
Synthetic Communications, 2006 , vol. 36, # 12 p. 1715 - 1719
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; 1,8-diazabicyclo[5.4.0]undec-7-ene in 1,4-dioxane
T=180°C; 0.166667 h; Microwave irradiationsealed tube;
参考文献
Hostyn, Steven; Van Baelen, Gitte; Lemiere, Guy L. F.; Maes, Bert U. W.
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2653 - 2660
反应条件
palladium diacetate; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene
Buchwald-Hartwig reaction; 18 h; Reflux; regioselective reaction;
参考文献
Hostyn, Steven; Van Baelen, Gitte; Lemiere, Guy L. F.; Maes, Bert U. W.
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2653 - 2660
反应条件
1: dicyclohexyl-carbodiimide / dichloromethane / 20 °C
2: copper(l) iodide; 1,10-phenanthroline; potassium acetate; tetrabutylammomium bromide / N,N-dimethyl-formamide / 10 h / 100 °C
View Scheme
参考文献
Sun, Jie; Tan, Qitao; Yang, Wusong; Liu, Bingxin; Xu, Bin
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 388 - 394
