4-溴-1,3-二甲基-1H-吡唑合成路线 （共 13 条）
反应条件
bromine in acetic acid T=20 - 100°C;
参考文献
Attaryan; Akopyan; Badalyan; Minasyan; Asratyan
Russian Journal of Organic Chemistry, 2007 , vol. 43, # 11 p. 1740 - 1741
反应条件
bromine in acetic acid T=70°C; 1 h;
参考文献
Andreeva, M. A.; Bolotov, M. I.; Isaev, Sh. G.; Mushii, R. Ya.; Perevalov, V. P.; et al.
J. Gen. Chem. USSR (Engl. Transl.), 1980 , vol. 50, # 9 p. 2116 - 2119,1714 - 1716
反应条件
sodium hydroxide; bromine in water T=20°C; 1 h;
参考文献
Attaryan; Akopyan; Badalyan; Asratyan
Russian Journal of General Chemistry, 2007 , vol. 77, # 2 p. 307 - 308
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 116, p. 93
参考文献
Justus Liebigs Annalen der Chemie, , vol. 458, p. 203
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 116, p. 93
反应条件
potassium permanganate in water T=60°C;
参考文献
Manaev, Yu. A.; Andreeva, M. A.; Perevalov, V. P.; Stepanov, B. I.; Dubrovskaya, V. A.; Seraya, V. I.
J. Gen. Chem. USSR (Engl. Transl.), 1982 , vol. 52, # 11 p. 2592 - 2598,2291 - 2296
反应条件
1: 61 percent / bromine / acetic acid / 1 h / 80 °C 2: 81 percent / 20percent oleum, conc. HNO3 / 2 h / 40 - 45 °C 3: 96 percent / 28percent ammonia / H2O / 4 h / 180 °C / sealed vessel View Scheme
参考文献
Andreeva, M. A.; Bolotov, M. I.; Isaev, Sh. G.; Mushii, R. Ya.; Perevalov, V. P.; et al.
J. Gen. Chem. USSR (Engl. Transl.), 1980 , vol. 50, # 9 p. 2116 - 2119,1714 - 1716
反应条件
1: 4-bromo-1,3-dimethyl-1H-pyrazole With tert.-butyl lithium in diethyl ether T=-78°C; 0.583333 h; Inert atmosphere; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in diethyl ether T=-78 - 25°C; 0.75 h; Inert atmosphere;
参考文献
WO2013/91096 A1, ;
Page/Page column 47 ;
反应条件
n-butyllithium in tetrahydrofuran T=-78 - 20°C; 1.08333 h;
参考文献
US2013/123281 A1, ;
Paragraph 0127; 0128 ;
