2-(4-溴苯基)-2-氧代乙酸甲酯合成路线 （共 12 条）
反应条件
in tetrahydrofuran T=20°C; Wittig reaction;
参考文献
Tetrahedron Letters, , vol. 46, # 51 p. 8949 - 8952
反应条件
in tetrahydrofuran T=20°C; Wittig reaction;
参考文献
Hamaguchi, Masashi; Iyama, Yuji; Mochizuki, Eiko; Oshima, Takumi
Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8949 - 8952
反应条件
water; diethylazodicarboxylate; dirhodium tetraacetate in toluene
4 h; Heating;
参考文献
Guo, Zhenqiu; Huang, Haoxi; Fu, Qingquan; Hu, Wenhao
Synlett, 2006 , # 15 p. 2486 - 2488
反应条件
1: para-bromoacetophenone With pyridine; selenium(IV) oxide
T=100°C; 15 h; Inert atmosphere;
2: methanol With thionyl chloride
T=20°C; Cooling with iceMolecular sieve;
3: With perchloric acid; water in acetonitrile
T=20°C; 0.5 h;
参考文献
Zhuang, Jing; Wang, Changqing; Xie, Fang; Zhang, Wanbin
Tetrahedron, 2009 , vol. 65, # 47 p. 9797 - 9800
反应条件
in tetrahydrofuran; diethyl ether
T=0 - 20°C;
参考文献
Sheppeck, James; Dhar, T.G. Murali; Doweyko, Lidia; Gilmore, John; Weinstein, David; Xiao, Hai-Yun; Yang, Bingwei V.; Doweyko, Arthur M.
Patent: US2006/154973 A1, 2006 ;
Location in patent: Page/Page column 47 ;
反应条件
sodium bromide in dichloromethane; water
Ambient temperatureanodic oxidation;
参考文献
Banerjee, Sudheer K.; Shanker, R.; Sachdeva, Om P.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1986 , vol. 41, # 4 p. 467 - 472
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; C34H24N2O2; oxygen; [Co(O2CCH3)2]*4H2O in toluene
T=60°C; P=760.051 Torr; 40 h; optical yield given as percent eeenantioselective reaction;
参考文献
Alamsetti, Santosh Kumar; Sekar, Govindasamy
Chemical Communications, 2010 , vol. 46, # 38 p. 7235 - 7237
反应条件
p-MeC6H4IF2; boron trifluoride diethyl etherate in chlorobenzene
T=110°C; 0.0833333 h;
参考文献
Tao, Jason; Tran, Richard; Murphy, Graham K.
Journal of the American Chemical Society, 2013 , vol. 135, # 44 p. 16312 - 16315
反应条件
in diethyl ether
T=-70°C;
参考文献
Cohen; Gibson; Fan; De la Cruz; Gitler; Hariman; Reba
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 4 p. 326 - 329
反应条件
1: HCl (gas) / diethyl ether / 1 h
2: water
View Scheme
参考文献
Muller, A. J.; Nishiyama, K.; Griffin, G. W.; Ishikawa, K.; Gibson, D. M.
Journal of Organic Chemistry, 1982 , vol. 47, # 12 p. 2342 - 2352
