2-溴-1,3-二甲苯合成路线 （共 189 条）
反应条件
tert-butyl N,N,N',N'-tetraisopropylphosphorodiamidite; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate in toluene T=105°C; Buchwald-Hartwig Coupling; 6 h; Inert atmosphereSchlenk technique;
参考文献
Roiban, Gheorghe-Doru; Mehler, Gerlinde; Reetz, Manfred T.
European Journal of Organic Chemistry, 2014 , vol. 2014, # 10 p. 2070 - 2076
反应条件
1: 2,4,6-trimethylphenylmagnesium bromide With PEPPSITM-IPr; zinc(II) chloride in tetrahydrofuran T=23°C; 0.333333 h; Inert atmosphere; 2: 1-bromo-2,6-dimethyl-benzene in tetrahydrofuran T=70°C; 2.5 h; Inert atmosphere;
参考文献
Calimsiz, Selcuk; Sayah, Mahmoud; Mallik, Debasis; Organ, Michael G.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 11 p. 2014 - 2017
反应条件
1: With isopropylmagnesium chloride in tetrahydrofuran T=0°C; Inert atmosphere; 2: With methanol in tetrahydrofuran Kinetics; ConcentrationTime;
参考文献
Shi, Lei; Chu, Yuanyuan; Knochel, Paul; Mayr, Herbert
Organic Letters, 2012 , vol. 14, # 10 p. 2602 - 2605
反应条件
1: With isopropylmagnesium chloride in tetrahydrofuran T=0°C; Inert atmosphere; 2: With methanol in tetrahydrofuran Kinetics; ConcentrationTime;
参考文献
Shi, Lei; Chu, Yuanyuan; Knochel, Paul; Mayr, Herbert
Organic Letters, 2012 , vol. 14, # 10 p. 2602 - 2605
反应条件
potassium phosphate; 18-crown-6 ether; bis(dibenzylideneacetone)-palladium(0); [(t-Bu)3PH]BF4 T=160°C; 8 h; Inert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 9 p. 1565 - 1574
反应条件
1: With isopropylmagnesium chloride lithium chloride complex in tetrahydrofuran T=0°C; 2: With methanol in tetrahydrofuran Reactivity;
参考文献
Shi, Lei; Chu, Yuanyuan; Knoechel, Paul; Mayr, Herbert
Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2760 - 2764
反应条件
1: With isopropylmagnesium chloride lithium chloride complex in tetrahydrofuran T=0°C; 2: With methanol in tetrahydrofuran Reactivity;
参考文献
Shi, Lei; Chu, Yuanyuan; Knoechel, Paul; Mayr, Herbert
Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2760 - 2764
反应条件
hydrogen; oxygen T=40°C; P=760 Torr; Irradiationeffect of further reagents; Product distributionMechanism;
参考文献
Cacace, Fulvio; Ciranni, Giovanna; Marzio, Annito Di
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 4 p. 775 - 780
反应条件
Pd[P(o-tol)3]2; CyPF-t-Bu; ammonia; sodium t-butanolate in 1,4-dioxane T=80°C; 15 h; Inert atmosphere;
参考文献
Vo, Giang D.; Hartwig, John F.
Journal of the American Chemical Society, 2009 , vol. 131, # 31 p. 11049 - 11061
反应条件
tris(dibenzylideneacetone)dipalladium (0); Ti-N complexes; (S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate in toluene T=90°C; 8 h;
参考文献
Journal of the American Chemical Society, , vol. 120, # 30 p. 7651 - 7652
