2-(2-甲基-1,3-二氧杂烷-2-基)乙醇合成路线 （共 18 条）
反应条件
pyridine; PPh3.Br2 T=-10 - 20°C; 1.5 h;
参考文献
Petroski, Richard J.
Synthetic Communications, 2002 , vol. 32, # 3 p. 449 - 455
反应条件
oxalic acid; silica gel in dichloromethane Ambient temperature;
参考文献
Hitchcock; Perron; Martin; Albizati
Synthesis, 1990 , # 11 p. 1059 - 1061
反应条件
1: 1.) tosylation; 2.) NaI View Scheme
参考文献
Ohta, Hiromichi; Ozaki, Kazuhiko; Tsuchihashi, Gen-ichi
Chemistry Letters, 1987 , p. 2225 - 2226
反应条件
hydrogen; palladium(II) hydroxide/carbon in methanol
T=20°C; 16 h;
参考文献
Eisai Co., Ltd.
Patent: US2007/10542 A1, 2007 ;
Location in patent: Page/Page column 84 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=0°C;
参考文献
Duhamel, Lucette; Ancel, Jean-Erick
Tetrahedron, 1992 , vol. 48, # 42 p. 9237 - 9250
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
0.166667 h; Ambient temperature;
参考文献
Arseniyadis, Simeon; Rico Ferreira, Maria Del Rosario; Del Moral, Jose Quilez; Hernando, Jose Ignacio Martin; Potier, Pierre; Toupet, Loic
Tetrahedron Asymmetry, 1998 , vol. 9, # 22 p. 4055 - 4071
参考文献
Rhone-Poulenc Sante
Patent: US4876370 A1, 1989 ;
反应条件
(2S,3S)-2,3-dihydroxybutanedioic acid in ethyl acetate
16 h; Heating;
参考文献
Petroski, Richard J.
Synthetic Communications, 2002 , vol. 32, # 3 p. 449 - 455
反应条件
1: With camphor-10-sulfonic acid in toluene
T=110°C; 2 h;
2: With lithium aluminium tetrahydride in tetrahydrofuran
T=20°C; 1 h;
参考文献
Raghavan, Sadagopan; Joseph, Suju C.
Tetrahedron Letters, 2003 , vol. 44, # 45 p. 8237 - 8239
反应条件
1: 94 percent / KOt-Bu / dimethylsulfoxide; methanol / 0.5 h / 20 °C
2: 90 percent / aq. OsO4; NMO / acetone / 19 h / 20 °C
View Scheme
参考文献
Mereyala, Hari Babu; Gurrala, Srinivas Reddy; Mohan, S. Krishna
Tetrahedron, 1999 , vol. 55, # 37 p. 11331 - 11342
