7-羟基-4-三氟甲基香豆素合成路线 （共 9 条）
反应条件
iodine in toluene T=80°C; Pechmann reaction;
参考文献
Wu, Jie; Diao, Tianning; Sun, Wei; Li, Yizhe
Synthetic Communications, 2006 , vol. 36, # 20 p. 2949 - 2956
反应条件
3 A molecular sieve T=120°C; Product distribution / selectivity;
参考文献
GRUeNENTHAL GMBH
Patent: WO2004/2980 A2, 2004 ;
Location in patent: Page/Page column 20-22 ;
反应条件
sulfuric acid in nitrobenzene Pechmann reaction;
参考文献
Bulletin of the Chemical Society of Ethiopia, , vol. 24, # 2 p. 305 - 310
反应条件
phosphoric acid; NADPH in methanol; water T=37°C; Hydrolysis; pH=7.4; 0.25 h; Enzymatic reaction; Enzyme kinetics; Further Variations:Reagentstime;
参考文献
Xenobiotica, , vol. 30, # 10 p. 955 - 969
反应条件
cytochrome P450 2C9 Enzymatic reaction;
参考文献
Acta Pharmacologica Sinica, , vol. 34, # 11 p. 1437 - 1448
反应条件
in acetonitrile T=24.84°C; pH=8; Irradiation; Kinetics;
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 37 p. 9344 - 9347
Angew. Chem., , vol. 124, # 37 p. 9478 - 9481,5
反应条件
potassium carbonate in acetone 24 h; Heating;
参考文献
Wanchana, Suchada; Yamashita, Fumiyoshi; Hashida, Mitsuru
Pharmaceutical Research, 2003 , vol. 20, # 9 p. 1401 - 1408
反应条件
1: 7-Hydroxy-4-(trifluoromethyl)-coumarin With sodium hydroxide 2: methyl 5-acetamido-4,7,8,9-tetra-OAc-2-chloro-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosylonate in N,N-dimethyl-formamide T=20°C; 4 h; Further stages.;
参考文献
Buchini, Sabrina; Buschiazzo, Alejandro; Withers, Stephen G.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 14 p. 2700 - 2703
反应条件
potassium carbonate; acetone
参考文献
Whalley
Journal of the Chemical Society, 1951 , p. 3235,3238
