1-甲基-2-(1-丙炔基)-苯合成路线 （共 11 条）
反应条件
lanthanum; iodine in tetrahydrofuran
T=67°C; Fritsch-Buttenberg-Wiechell rearrangement; 3 h; Inert atmosphere;
参考文献
Umeda, Rui; Yuasa, Takumi; Anahara, Namika; Nishiyama, Yutaka
Journal of Organometallic Chemistry, 2011 , vol. 696, # 9 p. 1916 - 1919
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine
T=50°C; 3 h;
参考文献
Fogel; Hsung; Wulff
Journal of the American Chemical Society, 2001 , vol. 123, # 23 p. 5580 - 5581
反应条件
1: H-CC-CH2-Mg-halogen With zinc dibromide in tetrahydrofuran
T=20°C; 0.25 h;
2: 1-iodo-2-methylbenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=20°C; 2 h; Further stages.;
参考文献
Weiss, Hilton M.; Touchette, Kim M.; Angell, Sarah; Khan, Jihan
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 12 p. 2152 - 2156
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride
24 deg C, then 65 deg C;
参考文献
Pschirer, Neil Gregory; Bunz, Uwe H. F.
Tetrahedron Letters, 1999 , vol. 40, # 13 p. 2481 - 2484
反应条件
1: 72 percent / PCl5 / 12 h / 20 °C
2: 45 percent / KOH / ethanol / Heating
3: 1.) Li, Fe(NO3)3 / 1.) liq.NH3, HMPA, 30 min; 2.) 6 h
View Scheme
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
反应条件
1: 45 percent / KOH / ethanol / Heating
2: 1.) Li, Fe(NO3)3 / 1.) liq.NH3, HMPA, 30 min; 2.) 6 h
View Scheme
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
反应条件
potassium tert-butylate
参考文献
Wolinsky,J. et al.
Journal of Organic Chemistry, 1976 , vol. 41, p. 745 - 750
反应条件
1: (i) Br2, Py, hexane, (ii) KOH, EtOH
2: KOtBu
View Scheme
参考文献
Wolinsky,J. et al.
Journal of Organic Chemistry, 1976 , vol. 41, p. 745 - 750
反应条件
lithium; iron nitrate (III)
1.) liq.NH3, HMPA, 30 min; 2.) 6 h; Yield given. Multistep reaction;
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
反应条件
(i), (ii) Na, DMSO; Multistep reaction;
参考文献
Becker,J.Y.
Journal of Organometallic Chemistry, 1976 , vol. 118, p. 247 - 252
