4-(4-叔丁基苯基)苯甲酸合成路线 (共 7 条)
反应条件
sodium hypobromide in 1,4-dioxane
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
1: FeCl3 / CS2 2: AlCl3 / nitrobenzene 3: aq. NaOBr / dioxane View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
1: AlCl3 / nitrobenzene 2: aq. NaOBr / dioxane View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
4-(N,N-dimethlyamino)pyridine; tetrakis(triphenylphosphine) palladium(0); dicyclohexyl-carbodiimide; trifluoroacetic acid; Wang resin Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 20 p. 3144 - 3150
反应条件
1: 4-bromo-4'-tert-butylbiphenyl With magnesium in tetrahydrofuran Grignard reaction; Reflux; 2: carbon dioxide in tetrahydrofuran 3: With hydrogenchloride in tetrahydrofuran; water
参考文献
Dalton Transactions, , vol. 40, # 27 p. 7153 - 7164
反应条件
Cs/Na/K alloy 1.) THF, -75 deg C, 38 s; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 47, # 15 p. 2928 - 2939
反应条件
potassium tert-butylate; lithium; methyl iodide 1.) THF, -75 deg C, 2.) 10.5 min; the other reagent and time; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 47, # 15 p. 2928 - 2939