4-乙酰基-4'-甲基联苯合成路线 （共 60 条）
反应条件
potassium phosphate; 3-(2,6-diisopropylphenyl)-1-(2-diphenylphosphanylbenzyl)-3H-imidazol-1-ium chloride; bis(η3-allyl-μ-chloropalladium(II)) in 1,4-dioxane T=80°C; Suzuki cross-coupling; 12 h;
参考文献
Wang, Ai-E.; Zhong, Jun; Xie, Jian-Hua; Li, Kai; Zhou, Qi-Lin
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 6 p. 595 - 598
反应条件
potassium fluoride; palladium diacetate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=20°C; Suzuki cross-coupling; 27 h;
参考文献
Littke, Adam F.; Dai, Chaoyang; Fu, Gregory C.
Journal of the American Chemical Society, 2000 , vol. 122, # 17 p. 4020 - 4028
反应条件
tetrabutylammomium bromide; nickel; sodium carbonate in ethanol T=80°C; Suzuki-Miyaura reaction; 6 h;
参考文献
You, Erli; Li, Pinhua; Wang, Lei
Synthesis, 2006 , # 9 p. 1465 - 1469
反应条件
C23H35N4O4Pd(1+)*Br(1-); potassium carbonate in water T=100°C; Suzuki-Miyaura Coupling; 1 h;
参考文献
Li, Liuyi; Wu, Tao; Wang, Jinyun; Wang, Ruihu
ChemPlusChem, 2014 , vol. 79, # 2 p. 257 - 265
反应条件
potassium hydroxide in water T=80°C; Suzuki coupling; 12 h;
参考文献
Ohtaka, Atsushi; Teratani, Takuto; Fujii, Ryohei; Ikeshita, Kanako; Kawashima, Takahiro; Tatsumi, Koichi; Shimomura, Osamu; Nomura, Ryoki
Journal of Organic Chemistry, 2011 , vol. 76, # 10 p. 4052 - 4060
反应条件
NHC-Pd(II)-Im; tetrabutyl ammonium fluoride in toluene T=120°C; Hiyama reaction; 3 h; Inert atmosphere;
参考文献
Gu, Zheng-Song; Shao, Li-Xiong; Lu, Jian-Mei
Journal of Organometallic Chemistry, 2012 , vol. 700, p. 132 - 134
反应条件
potassium carbonate in ethanol; water T=50°C; Suzuki-Miyaura Coupling; 1.5 h;
参考文献
Zhang, Qiang; Su, Hong; Luo, Jun; Wei, Yunyang
Tetrahedron, 2013 , vol. 69, # 2 p. 447 - 454
反应条件
sodium hydroxide; Pd(NH3)2Cl2 in water T=120°C; Hiyama coupling; 9 h;
参考文献
Chen, Shao-Nung; Wu, Wei-Yi; Tsai, Fu-Yu
Tetrahedron, 2008 , vol. 64, # 35 p. 8164 - 8168
反应条件
palladium diacetate in water; N,N-dimethyl-formamide T=20°C; 22 h;
参考文献
Yamamoto, Yasunori; Takizawa, Miho; Yu, Xiao-Qiang; Miyaura, Norio
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 928 - 931
反应条件
palladium diacetate in water; N,N-dimethyl-formamide T=20°C; 5 h;
参考文献
Yamamoto, Yasunori; Takizawa, Miho; Yu, Xiao-Qiang; Miyaura, Norio
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 928 - 931
