1: diisopropylamine, n-butyllithium / tetrahydrofuran; hexane / 1.) -78 deg C, 1 h, 2.)-78 deg C -> RT, 30 min 2: DDQ / CH2Cl2 / 1 h / Ambient temperature View Scheme

1: 6,7-dimethoxy-1H-benzo[d][1,3]oxazine-2,4-dione With sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 0.5 h; 2: methyl iodide in N,N-dimethyl-formamide T=0 - 20°C; 1 h;

copper diacetate; palladium diacetate; potassium iodide in acetonitrile T=20°C; P=760.051 Torr; regioselective reaction;

(i) NaH, AcNMe2, (ii) methyl halide; Multistep reaction;