2,2-二甲基-1,3-二氧戊环-4-甲酸合成路线 （共 10 条）
反应条件
potassium carbonate in acetone T=65°C; 4 h;
参考文献
Gravestock, Michael B.; Knight, David W.; Lovell, Jennifer S.; Thornton, Steven R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 13 p. 1661 - 1664
反应条件
in methanol; hexane; water; acetonitrile
参考文献
Yamaoka, Hidenori; Moriya, Narimasa; Ikunaka, Masaya
Organic Process Research and Development, 2004 , vol. 8, # 6 p. 931 - 938
参考文献
Hill, Alison M.; Harris, Jonathan P.; Siskos, Alexandros P.
Chemical Communications, 1998 , # 21 p. 2361 - 2362
反应条件
in methanol; water; acetonitrile pH=4; Acidic aqueous solution;
参考文献
Nagase & Co., Ltd.; Nagase Chemtex Corporation
Patent: JP2005/75784 A, 2005 ;
Location in patent: Page/Page column 16; 22 ;
反应条件
methanol; potassium hydroxide
T=0 - 20°C; 0.75 h;
参考文献
Rosseto, Renato; Hajdu, Joseph
Tetrahedron, 2014 , vol. 70, # 19 p. 3155 - 3165
反应条件
trichloroisocyanuric acid; tetrabutylammomium bromide; water; potassium carbonate; ruthenium trichloride in acetonitrile
T=20 - 45°C; 1 - 3 h; Product distribution / selectivity;
参考文献
Nagase & Co., Ltd.; Nagase Chemtex Corporation
Patent: JP2005/75784 A, 2005 ;
Location in patent: Page/Page column 16-17; 22 ;
反应条件
1: 80 percent / 0.4 M K2CO3 / H2O / 20 °C / electrolysis
2: electrolysis
3: 6 percent / electrolysis
View Scheme
参考文献
Schaefer, Hans J.; Schneider, Roy
Tetrahedron, 1991 , vol. 47, # 4-5 p. 715 - 724
反应条件
sodium hydroxide; Soerensen phosphate buffer; thermitase in water
T=33°C; 1.73333 h; kinetic resolution; Product distribution;
参考文献
Schick, Hans; Schroetter, Eberhard; Szymanowski, Matthias; Knoll, Alexander
Liebigs Annalen der Chemie, 1993 , # 1 p. 103 - 104
参考文献
Schaefer, Hans J.; Schneider, Roy
Tetrahedron, 1991 , vol. 47, # 4-5 p. 715 - 724
反应条件
1: electrolysis
2: 6 percent / electrolysis
View Scheme
参考文献
Schaefer, Hans J.; Schneider, Roy
Tetrahedron, 1991 , vol. 47, # 4-5 p. 715 - 724
