3,4-二氢-2H-1,4-苯并噁嗪合成路线 （共 21 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=125°C; 15 h;
参考文献
Mizar, Pushpak; Myrboh, Bekington
Tetrahedron Letters, 2006 , vol. 47, # 44 p. 7823 - 7826
反应条件
2-(di-t-butylphosphino)-1,1'-binaphthyl; palladium diacetate; caesium carbonate in toluene T=50°C; 24 h;
参考文献
Toracca, Karen E.; Kuwabe, Shin-Itsu; Buchwald, Stephen L.
Journal of the American Chemical Society, 2000 , vol. 122, # 51 p. 12907 - 12908
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran Heating / reflux; 2: With sodium hydroxide; water in tetrahydrofuran
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: US2008/200471 A1, 2008 ;
Location in patent: Page/Page column 47 ;
US 20080200471 A1
反应条件
1: With ozone in methanol T=-78°C; 2: With hydrogen; nitrobenzene; palladium on activated charcoal in methanol T=25°C; P=3040 Torr; 6 h;
参考文献
Bunce, Richard A.; Herron, Derrick M.; Hale, Lu Y.
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 6 p. 1031 - 1039
反应条件
1: With diisobutylaluminium hydride in hexane; dichloromethane T=0 - 20°C; Inert atmosphere; 2: With NAF in hexane; dichloromethane; water T=0°C; 0.5 h;
参考文献
Cho, Hidetsura; Iwama, Yusuke; Okano, Kentaro; Tokuyama, Hidetoshi
Chemical and Pharmaceutical Bulletin, 2014 , vol. 62, # 4 p. 354 - 363
反应条件
polymethylhydrosiloxane; palladium dihydroxide in ethanol T=20°C; 0.5 h;
参考文献
Reddy, Ch. Raji; Vijeender; Bhusan, P. Bibhuti; Madhavi, P. Phani; Chandrasekhar
Tetrahedron Letters, 2007 , vol. 48, # 15 p. 2765 - 2768
反应条件
naphthalene; tetraethylammonium bromide in N,N-dimethyl-formamide T=0°C; Inert atmosphereElectrolysis;
参考文献
Senboku, Hisanori; Nakahara, Kazuo; Fukuhara, Tsuyoshi; Hara, Shoji
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 435 - 438
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in toluene T=-40°C; 1.16667 h;
参考文献
Bartsch; Schwarz
Archiv der Pharmazie, 1982 , vol. 315, # 6 p. 538 - 545
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in ethyl acetate; benzene T=-40°C;
参考文献
Archiv der Pharmazie, , vol. 315, # 6 p. 538 - 545
反应条件
hydrogenchloride in acetonitrile
参考文献
Journal of Heterocyclic Chemistry, , vol. 43, # 4 p. 1125 - 1127
