3-溴-2-氧代-丁酸乙酯合成路线 （共 6 条）
反应条件
bromine in dichloromethane T=5 - 20°C;
参考文献
Macielag, Mark J.; Xia, Mingde; McNally, James J.; Matthews, Jay M.
Patent: US2012/149699 A1, 2012 ;
Location in patent: Page/Page column 14-15 ;
反应条件
N-bromosuccinmide in tetrachloromethane 5 h; Heating;
参考文献
Plouvier, Bertrand; Bailly, Christian; Houssin, Raymond; Henichart, Jean-Pierre
Heterocycles, 1991 , vol. 32, # 4 p. 693 - 701
反应条件
1: alpha-Ketobutyric acid With sulfuric acid in ethanol Reflux; 2: ethyl acetate With copper(ll) bromide in chloroform Reflux;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 17 p. 5124 - 5127
参考文献
Journal of the American Chemical Society, , vol. 76, p. 5796
反应条件
in water 1.) reflux, 15 min, 2.) RT, 12 h;
参考文献
Plouvier, Bertrand; Bailly, Christian; Houssin, Raymond; Henichart, Jean-Pierre
Heterocycles, 1991 , vol. 32, # 4 p. 693 - 701
参考文献
Cornwall, Philip; Dell, Colin P.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 10 p. 2417 - 2428
