1-(2'-硝基[1,1'-联苯]-4-基)乙烷-1-酮合成路线 （共 17 条）
反应条件
sodium hypobromide in 1,4-dioxane
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
triethyl phosphite T=210°C; Cadogan cyclization; 0.166667 h; microwave irradiation;
参考文献
Appukkuttan, Prasad; Van Der Eycken, Erik; Dehaen, Wim
Synlett, 2005 , # 1 art. no. G33904ST, p. 127 - 133
反应条件
carbon disulfide; aluminium trichloride
T=45 - 50°C;
参考文献
Grieve; Hey
Journal of the Chemical Society, 1933 , p. 968,971
反应条件
bis(acetylacetonato) palladium; N,N,N',N,-tetramethylethylenediamine; copper(I) bromide in 1-methyl-pyrrolidin-2-one
T=170°C; 3 h; Inert atmosphere; chemoselective reaction;
参考文献
Cahiez, Gerard; Moyeux, Alban; Gager, Olivier; Poizat, Mael
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 790 - 796
反应条件
1: ortho-nitrobenzoic acid With cupric(II) carbonate in various solvent(s)
T=120°C; 0.5 h;
2: para-bromoacetophenone With potassium fluoride; palladium acetylacetonate; iso-propyldiphenylphoshine in various solvent(s)
T=120°C; 24 h; Further stages.;
参考文献
Goossen, Lukas J.; Rodriguez, Nuria; Melzer, Bettina; Linder, Christophe; Deng, Guojun; Levy, Laura M.
Journal of the American Chemical Society, 2007 , vol. 129, # 15 p. 4824 - 4833
反应条件
quinoline; bis(acetylacetonato) palladium; copper(l) iodide; biphenyl-2-yl-di-tert-butyl-phosphane in 1-methyl-pyrrolidin-2-one
T=160°C; 24 h; Inert atmosphere;
参考文献
Goossen, Lukas J.; Zimmermann, Bettina; Knauber, Thomas
Angewandte Chemie - International Edition, 2008 , vol. 47, # 37 p. 7103 - 7106
反应条件
sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=150°C; Suzuki-Miyaura cross-coupling reaction; 0.166667 h; microwave irradiation;
参考文献
Appukkuttan, Prasad; Van Der Eycken, Erik; Dehaen, Wim
Synlett, 2005 , # 1 art. no. G33904ST, p. 127 - 133
反应条件
[Cu(Phen)(PPh3)2]NO3; potassium tert-butylate; palladium diacetate in 1-methyl-pyrrolidin-2-one
T=170°C; 1 h; SonicationContinuous flow reactor;
参考文献
Lange, Paul P.; Goossen, Lukas J.; Podmore, Philip; Underwood, Toby; Sciammetta, Nunzio
Chemical Communications, 2011 , vol. 47, # 12 p. 3628 - 3630
反应条件
palladium (II) trifluoroacetate; silver carbonate in dimethyl sulfoxide
T=120°C; Suzuki coupling; 2 h;
参考文献
Dai, Jian-Jun; Liu, Jing-Hui; Luo, Dong-Fen; Liu, Lei
Chemical Communications, 2011 , vol. 47, # 2 p. 677 - 679
反应条件
2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; N,N-dimethyl-aniline; silver carbonate; palladium dichloride
T=150°C; 2 h;
参考文献
Wang, Zhiyong; Ding, Qiuping; He, Xiaodan; Wu, Jie
Tetrahedron, 2009 , vol. 65, # 24 p. 4635 - 4638
